Clinical application of targeted next ‐generation sequencing on fetuses with congenital heart defects

ConclusionsTargeted NGS of fetuses with isolated and non‐isolated CHDs achieved a high diagnostic yield in our cohort, with an acceptable turnaround time for the prenatal setting. Our results have important implications for clinical management and genetic counseling.

Source: Ultrasound in Obstetrics and Gynecology - March 1, 2018 Category: Radiology Authors: Ping Hu, Fengchang Qiao, Yan Wang, Lulu Meng, Xiuqing Ji, Chunyu Luo, Tianhui Xu, Ran Zhou, Jingjing Zhang, Bin Yu, Leilei Wang, Ting Wang, Qiong Pan, Dingyuan Ma, Dong Liang, Zhengfeng Xu Tags: Original Paper Source Type: research