Status epilepticus: Recent advances.

[Status epilepticus: Recent advances]. Presse Med. 2018 Mar 08;: Authors: Szurhaj W, Engrand N Abstract About half of status epilepticus (SE) occur in patients without epilepsy. An EEG has to be performed quickly in any patient who remains unconscious after the end of convulsions with the aim to detect a subtle status. An EEG should be performed as soon as possible in case of suspicion of non-convulsive status epilepticus, or in case of a confusional state whose origin remains unknown. The realization of a cerebral imaging is very often necessary in case of inaugural SE, as soon as the patient's condition allow it. It is also often indicated in case of known epilepsy. The main differential diagnosis of convulsive SE is psychogenic non-epileptic status. In non-convulsive status epilepticus, the use of anesthetic agents should be considered only rarely, as the risks of such an approach are often greater than the expected benefits. PMID: 29526428 [PubMed - as supplied by publisher]
Source: Presse Medicale - Category: General Medicine Authors: Tags: Presse Med Source Type: research

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Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Top Med Chem Source Type: research
Publication date: Available online 8 November 2019Source: Epilepsy &BehaviorAuthor(s): Sara HockerAbstractThe epidemiology of status epilepticus (SE) and predictors of outcome in particular have been well described with consistent findings around the world. Understanding of the actual causes of death in patients hospitalized with SE is limited. The following is a summary of published information about causes of death in patients hospitalized with SE and a reconciling of conflicting studies examining the influence of continuous intravenous anesthetic drugs on the mortality of SE. A recently published paper was presented...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Status epilepticus (SE) represents a neurological emergency that requires urgent treatment and rapid escalation of care if symptoms do not subside within a short time from onset [1]. The progression to Refractory Status Epilepticus (RSE) is reported in 40% of SE cases (Rossetti and Lowenstein. 2011), often requiring intravenous anaesthetic treatment (IVAT) and critical care admission [2]. RSE, though, still associates with substantial morbidity and mortality [3 –5].
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research
Abstract The epidemiology of status epilepticus (SE) and predictors of outcome in particular have been well described with consistent findings around the world. Understanding of the actual causes of death in patients hospitalized with SE is limited. The following is a summary of published information about causes of death in patients hospitalized with SE and a reconciling of conflicting studies examining the influence of continuous intravenous anesthetic drugs on the mortality of SE. A recently published paper was presented at the Colloquium and is summarized here, along with new data addressing an audience questi...
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
This article presents a super obese patient (BMI 57 kg/m2) with drug-refractory epilepsy and obstructive sleep apnea who underwent left anterior temporal lobectomy through awake craniotomy to preserve language and memory, using warmed humidified high flow nasal cannula (HFNC) oxygen therapy. Awake craniotomy was facilitated by the use of HFNC, which proved essential to prevent airway collapse by creating continuous positive airway pressure through high flow and facilitated intraoperative neurologic language and memory testing while maintaining adequate oxygenation. PMID: 31686115 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research
This article is part of the Special Issue “Proceedings of the 7th London-Innsbruck Colloquium on Status Epilepticus and Acute Seizures”.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
This article is part of the Special Issue "Proceedings of the 7th London-Innsbruck Colloquium on Status Epilepticus and Acute Seizures". PMID: 31676239 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
Publication date: Available online 22 October 2019Source: SeizureAuthor(s): Donald P. Craig, Tejal N. Mitchell, Rhys H. ThomasAbstractIn status epilepticus the imperative to start anti-seizure therapy, initially subjugates the need to investigate the cause. Once treatment is initiated this balance shifts in favour of identifying: the causes and consequences of the seizure; the factors that predetermined the occurrence of status epilepticus; and finally the prognosis of this acute episode. Just as there are multiple causes of seizures and epilepsy, there are a vast number of causes of status epilepticus. We discuss the more...
Source: Seizure - Category: Neurology Source Type: research
Conclusion: The conclusion drawn from this systematic review will benefit the children with or without epilepsy undergoing sevoflurane anesthesia. Ethics and dissemination: Ethics approval is unnecessary because data of individual patients will not be included and no privacy will be involved. The results of this review will be published in a peer-reviewed journal or a conference report. Amendments of the basic protocol will be documented in the comprehensive review. PROSPERO registration number: PROSPERO CRD 42019122008.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Status epilepticus is a common neurological emergency, with overall mortality around 20%. Over half of cases are first time presentations of seizures. The pathological process by which spontaneous seizures are generated arises from an imbalance in excitatory and inhibitory neuronal networks, which if unchecked, can result in alterations in intracellular signalling pathways and electrolyte shifts, which bring about changes in the blood brain barrier, neuronal cell death and eventually cerebral atrophy.
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Tags: Review Source Type: research
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