Discussion

Dr Bryan M. Burt (Houston, Tex). Boris, I very much enjoyed listening to your talk and reading your paper. In brief summary, your group retrospectively evaluated these tagging and potentially functional SNPs in 266 cytokine signaling pathway genes in the peripheral blood, which I will emphasize are germline SNPs, and this is among a robust cohort of 722 patients who were treated surgically for non –small cell lung cancer at your institution. You have shown to us that a handful of these SNPs were independently associated with recurrence-free survival, either better survival and another handful with worse survival, and the same thing for overall survival, and you have implied that these data might have potentially prognostic importance for patients with non–small cell lung cancer who are treated surgically.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research