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Evidence that Extreme Dilutions of Paclitaxel and Docetaxel Alter Gene Expression of In Vitro Breast Cancer Cells.

This study investigated the effects of ultramolecular dilution of the taxane anti-cancer drugs, which are not commonly used in homeopathic medicines, on mRNA expression profiles of five key genes (p53, p21, COX-2, TUBB2A and TUBB3) in the breast cancer cell line MCF-7. METHOD:  MCF-7 cells were exposed to paclitaxel (Taxol) or docetaxel (Taxotere) preparations (6X, 5C and 15C dilutions prepared from pharmacological concentration of 25 nmol/L) for 72 hours. The cell culture groups were evaluated with the trypan blue dye exclusion method for the proliferation/cytotoxicity rates, immuno-staining β-tubulin for microtubule organization, and reverse transcription polymerase chain reaction for gene expression levels.Fold-change in gene expression was determined by the ΔΔCt method. RESULTS:  The administration of diluted preparations had little or no cytotoxic effect on MCF-7 cells, but altered the expression of genes analyzed with a complex effect. According to the ΔΔCt method with a five-fold expression difference (p 
Source: Homeopathy - Category: Complementary Medicine Authors: Tags: Homeopathy Source Type: research

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Cancer patients who opt for alternative therapy instead of conventional medicine significantly decrease their chances of survival, according to researchers at Yale School of Medicine. Although the popularity of alternative medicine continues to grow, a recent study published in the Journal of the National Cancer Institute found survival rates significantly reduced for those who use it as first-line therapy. Conventional cancer treatments — chemotherapy, surgery and radiation — still produce a much better chance of survival. Mesothelioma was not included in the study, but the findings are relevant to this rare ...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Tags: acupuncture cancer Alternative medicine alternative mesothelioma treatment alternative therapy survival alternative vs conventional medicine breast cancer colon cancer Conventional cancer treatments Dr. David Gorski Dr. Skyler Johnson Source Type: news
Conclusion The results and conclusions of this study are clear: people who choose conventional treatments for cancer (such as surgery, radiotherapy, chemotherapy and hormone treatments) are likely to live longer than those who choose alternative medicine only. It's rare for people to choose to ignore conventional treatment completely when faced with a cancer diagnosis. More often, people choose to add complementary therapies to their conventional cancer treatment. This study doesn't apply to people combining conventional and complementary therapies. There are some limitations to the study to be aware of: As an observatio...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Source Type: news
Researchers from Yale School of Medicine found that breast cancer sufferers who rely on herbs, homeopathy or energy crystals to heal are 5.68 times more at risk of death in five years.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Just over two years ago, the Society for Integrative Medicine issued clinical guidelines for breast cancer care. Now it's updated them. Unfortunately, mixing cow pie with apple pie for a little longer doesn't make the cow pie any better than it was last time.
Source: Respectful Insolence - Category: Surgery Authors: Tags: Cancer Clinical trials Complementary and alternative medicine Homeopathy Naturopathy Quackery acupuncture breast cancer Dugald Seely Heather Greenlee integrative medicine integrative oncology society for integrative oncology Suza Source Type: blogs
I like to refer to homeopathy as The One Quackery To Rule Them All, so much so that I almost always call it that within the first two paragraphs of any post I write about some tasty bit of homeopathy pseudoscience. It’s also a wonderful tool for teaching critical thinking because it’s easy to explain…
Source: Respectful Insolence - Category: Surgery Authors: Tags: Cancer Clinical trials Complementary and alternative medicine Homeopathy breast cancer mastectomy quackademic medicine quackery Source Type: blogs
CONCLUSION: The current study reports the anticancer activity of homeopathic preparations of TC against breast cancer and reveals their nanoparticulate nature. These preliminary results warrant further mechanistic studies at both in vitro and in vivo levels to evaluate the potential of TC as nanomedicine in breast cancer. PMID: 27914571 [PubMed - in process]
Source: Homeopathy - Category: Complementary Medicine Authors: Tags: Homeopathy Source Type: research
CONCLUSION: These preliminary results suggest that treatment with Ruta graveolens 5CH and Rhus toxicodendron 9CH may decrease joint pain/stiffness in breast cancer patients treated with AIs. A larger-scale randomized study is required to confirm these results. PMID: 27914569 [PubMed - in process]
Source: Homeopathy - Category: Complementary Medicine Authors: Tags: Homeopathy Source Type: research
Condition:   Breast Cancer Interventions:   Other: Homeopathy remedy;   Radiation: Radiation as adjuvant therapy for breast cancer Sponsors:   Sheba Medical Center;   Technion, Israel Institute of Technology Recruiting - verified August 2016
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Over the years, I’ve taken care of women with locally advanced breast cancer so advanced that it’s eroded through the skin, forming huge, nasty ulcers filled with stinky dead cancer tissue that’s outgrown its blood supply, leaving the patient in chronic pain. If the patient is fortunate, her cancer has not metastasized beyond her axillary…
Source: Respectful Insolence - Category: Surgery Authors: Tags: Complementary and alternative medicine Naturopathy Pseudoscience Quackery Skepticism/critical thinking Andy Schor antivaccine Brandon Dillon detoxification Doug Cutler George Darany HB 4531 homeopathy House Bill 4531 House of R Source Type: blogs
Conclusion Hep C 30 has demonstrable anticancer effects against liver cancer cells in vitro.
Source: Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
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