Evaluation of vaccination efficiency against HBV among Syrian multitransfused patients.

Evaluation of vaccination efficiency against HBV among Syrian multitransfused patients.
East Mediterr Health J. 2018 Mar 05;23(12):850-853
Authors: Yazji W, Habal W, Menem F
Abstract
This cross-sectional study estimates HBV prevalence and evaluates vaccination efficiency among multitransfused patients. 159 patients with various hemoglobinopathies were tested for HBsAg, anti-HBs, and anti-HBc, using enzyme-linked immunosorbent assay (ELISA). The serological results were then compared with the relevant documentation in medical records. Seropositivity of HBV was detected in 1/8 of recruited patients. Serological immunity was found in only half of patients, while the other half were either infected or non-immune. The vaccination against HBV appeared inefficient in almost half of vaccinated patients and was not documented in the medical records of 1/6 of patients. Thus, multitransfused patients are at risk of acquiring hepatitis B infection. Applying prophylactic vaccination, documenting vaccine doses, and monitoring immune response are highly recommended.
PMID: 29528096 [PubMed - in process]

Source: Eastern Mediterranean Health Journal - March 13, 2018 Category: Middle East Health Tags: East Mediterr Health J Source Type: research