AACE/ACE Statement on Biologics for Endocrine Diseases AACE/ACE Statement on Biologics for Endocrine Diseases
A new position statement provides guidance for endocrinologists regarding the use of biosimilars or follow-on biologics.Endocrine Practice
CONCLUSION: No significant difference was observed between the stroke patients and controls in terms of genotypes and allele distributions. Double combine haplotype CCAA was found to be protective against ischemic stroke when compare to other haplotypes. However, different genotypes of GSTO1 and GSTO2 were observed to have effects on stroke risk in subgroups of diabetics and smokers. In conclusion, the current study is the first to report this finding. PMID: 30417762 [PubMed - as supplied by publisher]
Publication date: Available online 14 November 2018Source: Life SciencesAuthor(s): Simone Marcieli Sartoretto, Fernanda Fernandes Santos, Beatriz Pereira Costa, Graziela Scalianti Ceravolo, Rosângela Santos-Eichler, Maria Helena Catelli Carvalho, Zuleica Bruno Fortes, Eliana Hiromi AkamineAbstractAimsInflammation is involved in diabetes-related vascular dysfunction. Estrogen receptor ESR2/ERβ induces the expression of inducible nitric oxide (NO) synthase (iNOS) and inflammation. The present study investigated the effect of alloxan-induced type 1 diabetes on the iNOS and ESR2 expression and the effect of the chro...
Supramolecular structure binds glucose strongly and selectively, pointing to future incorporation into diabetes treatment devices
Authors: Mora-Guzmán I, Martín-Pérez E Abstract Streptococcus bovis is an uncommon cause of biliary tract infection, being acute cholecystitis including this microorganism extremely rare. This entity is more frequent in older patients with cardiovascular disease, diabetes, hepatitis, or neoplasms as colon cancer. PMID: 30421958 [PubMed - as supplied by publisher]
Conclusion: Despite increases in age at the time of KT, the absolute risk of perioperative MACEs has remained stable from 2004 to 2013. HF is a major component of postoperative MACEs in KT. Malnutrition and pulmonary hypertension are major nontraditional predictors of perioperative MACE outcomes.Cardiorenal Med 2019;9:51 –60
Conclusions: Lesions at the PD catheter exit site are usually treated for infections. However, for ulcers that are painful, rapidly expanding, nonhealing, and unresponsive to antibiotics, PG should be considered as a differential diagnosis. This is the first reported case of PG occurring at the exit site of a PD catheter.Case Rep Nephrol Dial 2018;8:239 –245
AbstractBackgroundTransforming growth factor- β1 (TGF-β1) is a multifunctional cytokine that has numerous biological processes. Earlier research indicates that protein and mRNA production of TGF-β1 are enhanced in the renal tissues of patients with diabetic nephropathy (DN). Our aim was to evaluate the role of TGF-β1 in early prediction of DN in children with type 1 diabetes mellitus (T1DM).MethodsFifty patients with T1DM were enrolled in an observational study. Patients were eligible to participate if at least 3 years had passed since T1DM diagnosis. Patients were classified into two groups (A and B) a...
Authors: Macut D, Milutinović DV, Rašić-Marković A, Nestorov J, Bjekić-Macut J, Stanojlović O Abstract Over the last decade, huge achievements have been made in the fields of neurophysiology, molecular endocrinology, and biochemistry, as well as in the successful translation of clinical research into diseases into clinical practice. As regards female reproduction, most of the advances made in this area were achieved in gonadal axis regulation, regulation of behavior through sex steroids, reproductive genetics, preservation of ovarian reproductive function, steroid profiling, and metabolic and overall re...
A secondary analysis of CARMELINA trial data with linagliptin underlines that DDP-4 inhibitors are not linked to an increase in heart failure outcomes in patients with type 2 diabetes, say US researchers.Medscape Medical News
Condition: Lens Diseases Intervention: Device: slit lamp Sponsor: Assiut University Not yet recruiting