J & J, Macleods in talks for licence deal of tuberculosis drug
The talks, which are in early stage, will allow Macleods to manufacture generic version of the drug, a move if goes through will improve access to this new TB drug.
The unnamed man, 38, was treated at Wexham Park Hospital, Frimley. Scan shows a small 3x5mm lump in his right testicle, which sparked fears he may be suffering from cancer.
Culture-negative pulmonary tuberculosis (TB) is under-recognized and can lead to untreated disease, researchers say.Reuters Health Information
No abstract available
Publication date: Available online 20 February 2019Source: American Journal of Infection ControlAuthor(s): Qasim A. Mohiuddin, Leighanne Parkes, Michael GardamActive pulmonary tuberculosis testing with 3 expectorated sputa can increase isolation days and expenditures compared with 1 induced sputum. Six-month retrospective and prospective chart reviews were conducted, and a screening algorithm was phased into 2 hospital sites. With induced sputum testing, isolation decreased from 7 to 4 days (interquartile range, 4-3, P = .0135), and there was a cost savings of $7,275 per case, with no added harm.
Inf órmese sobre esta enfermedad contagiosa que se esparce mediante el aire por las bacterias. Puede ser mortal y afectar a cualquier persona en cualquier parte del mundo, pero es más común en los jóvenes de los países subdesarrollados. Descubra las causas, así como la forma de prevenirla y evitar la.
Contributors : Wang Xin ; Hussain SeemaSeries Type : Expression profiling by high throughput sequencingOrganism : Mycobacterium tuberculosisWe applied RNAseq (Nextseq) technology to study mechanism of action of nitro-containing heterocycle antitubercular JSF-2019, with des-nitro JSF-2026 as control. Briefly, mid-log phase (OD = 0.3) M. tuberculosis culture was treated by 10x MIC of each compound in biological quadruplicates followed by mRNA extraction and RNAseq analysis. We find that JSF-2019 and pretomanid as intracellular NO • donors exhibited distinct transcriptional patterns comparing to extracellular iNOS induce...
Microbial Drug Resistance, Ahead of Print.
This study aimed to understand the perception of TB among people originating from a high-endemic region, currently living in a low-endemic region. A qualitative study design, with male and female participants from a high-endemic region divided into focus groups. A semi-structured interview guide was used to elicit their perceptions of TB. A qualitative content analysis was performed on the recorded material from the interviews. The informants noted that their attitude towards individuals with TB had changed, previously they had felt prejudiced towards them whereas now they felt supportive. It seems possible to diminish TB ...
Tuberculosis (TB) is the ninth leading cause of deaths worldwide with an estimated 10 million new cases and 1.3 million deaths in 2017.1 Detection of acid-fast bacilli (AFB) using smear microscopy from clinical specimen is the most popular method for TB diagnosis worldwide, however, 30-60% of all pulmonary TB (PTB) cases in many high incidence settings are smear-negative.2 According to the 2018 global tuberculosis report of the World Health Organization (WHO), the mortality rate for smear-negative PTB can reach up to 20%, which might largely be caused by delay in diagnosis.