DIY cystitis therapy could end misery for thousands of women

From the age of 15, Mia Elderkvist suffered from repeated urinary tract infections which blighted her life. But a simple way of administering treatment changed her life.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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A female urethral diverticulum is a focal outpouching of the urethra into the urethrovaginal potential space.1 The reported incidence of urethral diverticula in women is approximately 1% to 6%, with the diagnosis typically occurring between the third and sixth decades of life.2 In symptomatic women, the classic clinical triad of dysuria, dyspareunia, and postvoid dribbling is present (the “three Ds”).1 However, women with urethral diverticula are more commonly asymptomatic or present with an array of nonspecific genitourinary symptoms such as urinary frequency and urgency, chronic or recurrent urinary tract inf...
Source: Contemporary Diagnostic Radiology - Category: Radiology Tags: ARTICLE Source Type: research
At least half of all adult women will experience infective cystitis (urinary tract infection: UTI) at least once in their life and many suffer from repeated episodes. Recurrent urinary tract infection (rUTI) i...
Source: Trials - Category: General Medicine Authors: Tags: Study protocol Source Type: research
The objective of this study was to investigate whether a single aminoglycoside dose adequately treated UTI.Methods: A systematic search of PubMed/MEDLINE and Google Scholar databases was performed through September 2018 for English-language original research articles assessing the efficacy of one-time parenteral aminoglycoside as UTI monotherapy.Results: Of 252 potentially relevant studies, 13 met inclusion criteria, representing 13,804 patients. Patient age ranged from 2 weeks to>70 years; both inpatient and outpatient settings were represented. Cystitis was more common than pyelonephritis and more females were represe...
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research
CONCLUSIONS: Antibiotic susceptibility in UTI is lower than reported in metropolitan France without evidence for an excessive consumption of antibiotics. PMID: 30385068 [PubMed - as supplied by publisher]
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
Publication date: Available online 3 November 2018Source: IDCasesAuthor(s): Kiyozumi Suzuki, Tetsuo Yamaguchi, Mitsuru YanaiAbstractEmphysematous prostatic abscess is a rare clinical entity of uncomplicated urinary tract infections with high mortality rate. Here we report a case of hypermucoviscous Klebsiella pneumoniae causing emphysematous prostatic abscess, emphysematous cystitis, and renal abscess simultaneously in a 75-year-old Japanese male with diabetes mellitus and advanced gastric cancer. The patient was successfully treated with prolonged intravenous antimicrobial agents.
Source: IDCases - Category: Infectious Diseases Source Type: research
This guideline sets out an antimicrobial prescribing strategy for lower urinary tract infection (also called cystitis) in children, young people and adults who do not have a catheter. It aims to optimise antibiotic use and reduce antibiotic resistance. It was published in October 2018.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Fosfomycin is a cell-wall active antibiotic with bactericidal activity against many gram-positive and negative bacteria. One dose of 3g oral Fosfomycin is indicated for uncomplicated cystitis in females [1]. Increasingly, it is used to treat cystitis caused by drug-resistant organisms but data on patients with renal impairment are lacking. We conducted a retrospective study to determine the safety and efficacy of fosfomycin in treating cystitis caused by extended spectrum beta-lactamase (ESBL) Enterobacteriaceae in a 1400-bed teaching hospital.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research
Uropathogenic Escherichia coli (UPEC) is the causative bacterium in most urinary tract infections (UTIs). UPEC cells adhere to and invade bladder epithelial cells (BECs) and cause uropathogenicity. Invading UPEC cells may encounter one of several fates, including degradation in the lysosome, expulsion to the extracellular milieu for clearance, or survival as an intracellular bacterial community and quiescent intracellular reservoir that can cause later infections. Here we considered the possibility that UPEC cells secrete factors that activate specific host cell signaling networks to facilitate the UPEC invasion of BECs. U...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Microbiology Source Type: research
We present a case of a 14-year-old girl who presented at our hospital 2 weeks after uncomplicated laparoscopic appendectomy. The girl complained of reduced urinary frequency and prolonged micturition time. Following an acute cystitis 2 months later, she completely lost her ability to void. A comprehensive set of investigations to assess the cause of her urinary retention including a cerebral and spinal magnetic resonance imaging (MRI), and videourodynamics were performed. The diagnostic workup revealed polycystic ovaries and an asensitive and hypotonic bladder with capacity up to 1200 mL and high maximum urethral pressure ...
Source: European Journal of Pediatric Surgery Reports - Category: Surgery Authors: Tags: Case Report Source Type: research
This study sought to provide direct evidence of the benefits of drinking extra fluids. What did the study tell us? The study participants were 140 premenopausal women who experienced three or more episodes of cystitis in one year and reported that they drank less than 1.5 liters of fluids daily, which is about 6 1/3 cups. The average amount participants drank daily was a bit over a liter (1.1 liters, or about 4 1/2 cups). The women were randomized to one of two groups. Every day, one group drank their usual amount of fluids plus an additional 1.5 liters of water. The control group drank just their usual amount of fluids. T...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Kidney and urinary tract Prevention Sex Women's Health Source Type: blogs
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