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Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout

New England Journal of Medicine, Ahead of Print.
Source: New England Journal of Medicine - Category: Internal Medicine Source Type: research

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This article summarizes the use of advanced imaging techniques in the diagnosis and assessment of gout and other crystal arthropathies. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Musculoskeletal Radiology - Category: Radiology Authors: Tags: Review Article Source Type: research
AbstractPurpose of ReviewCurrent evidence and accumulated experience for the management of calcium pyrophosphate deposition disease (CPPD) are presented.Recent FindingsContrary to other rheumatic inflammatory conditions that account for high interest and growing research, advances in treating CPPD are still very limited and mostly derive from those achieved in gout.SummaryOnce formed, calcium pyrophosphate crystals cannot be dissolved; therefore, management relies on the control of crystal-derived inflammation. Besides classical agents —such as colchicine, glucocorticoids, or NSAIDs—the use of targeted therapie...
Source: Current Rheumatology Reports - Category: Rheumatology Source Type: research
Siemens Healthineers is on an FDA clearing streak of its newest CT scanners. The latest news, following up clearances of the SOMATOM Force and SOMATOM Edge Plus, is that SOMATOM go.All and SOMATOM go.Top can also now be marke...
Source: Medgadget - Category: Medical Devices Authors: Tags: Emergency Medicine Neurosurgery Radiology Source Type: blogs
We report an unusual case of a calcifying aponeurotic fibroma with diffuse intra-articular involvement of the carpal joints in a 59-year-old female. Radiographs and computed tomography scans revealed a large lobulated soft tissue mass with multiple stippled calcifications around the carpal joints and numerous erosions of the second to fifth carpometacarpal and intercarpal joints. Magnetic resonance imaging showed diffuse multinodular synovial proliferation with inhomogeneous hypo- to isointense signal intensity on T1-weighted images, inhomogeneous hypointense to hyperintense signal intensity on T2-weighted images, and inho...
Source: Skeletal Radiology - Category: Radiology Source Type: research
Gout patients can now measure uric acid levels at home, and receive results in 30 seconds.(PRWeb April 17, 2018)Read the full story at http://www.prweb.com/releases/2018/04/prweb15405939.htm
Source: PRWeb: Medical Pharmaceuticals - Category: Pharmaceuticals Source Type: news
Source: Gait and Posture - Category: Orthopaedics Authors: Tags: Short communication Source Type: research
AbstractThis paper explores the importance of hope as a determining factor for patients to participate in first-in-human trials for synthetic biology therapies. This paper focuses on different aspects of hope in the context of human health and well-being and explores the varieties of hope expressed by patients. The research findings are based on interview data collected from stable gout and diabetes patients. Three concepts of hope have emerged from the interviews: hope as certainty (H1); hope as reflective uncertainty (H2); hope as self-therapy (H3). The purpose of the paper is twofold. First, it aims to underline the sig...
Source: Journal of Bioethical Inquiry - Category: Medical Ethics Source Type: research
Abstract OBJECTIVE: Our aim was to examine the prevalence of cardiovascular disease (CVD) in patients with crystal-proven gout compared to arthritis controls. Further, we analyzed the association between characteristic gout severity factors and CVD to provide further support for a pathogenetic relationship between gout and CVD. METHODS: Patients with arthritis referred for diagnosis were consecutively included in the Gout Arnhem-Liemers cohort. Joint fluid analysis was performed in all referred patients; controls were negative for crystals. Patients' characteristics and different manifestations of CVD and gou...
Source: J Rheumatol - Category: Rheumatology Authors: Tags: J Rheumatol Source Type: research
Conclusion Anakinra may be a safe therapeutic option for gout patients with advanced CKD. Further randomized controlled studies are required to confirm our results.
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Diagnostic Cytopathology, EarlyView.
Source: Diagnostic Cytopathology - Category: Pathology Authors: Source Type: research
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