Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure
New England Journal of Medicine, Ahead of Print.
Conclusion: These results suggest that CPS technology accurately quantifies heart and respiration rates and measure fluid change- in the lungs. Significance: The CPS has the potential to accurately monitor lung fluid status noninvasively and continuously in a clinical and outpatient setting. Early and efficient management of lung fluid status is key in managing chronic conditions such heart failure, pulmonary hypertension, and acute respiration distress syndrome.
Conclusions Left atrial volume decreases significantly following surgical relief of left ventricular outflow tract obstruction. Early changes likely reflect lower LA pressure due to gradient relief and abolishment of mitral regurgitation, and late reduction suggests continued reverse remodeling.
Patients with end-stage heart failure may not be aware that their ICDs can be deactivated as they near the end of life.Medscape Nurses
Authors: Pitt B, Garza D Abstract INTRODUCTION: Hyperkalemia (HK) occurs often among patients with chronic kidney disease (CKD) and heart failure (HF) and those treated with renin-angiotensin-aldosterone system inhibitors (RAASI). Even small deviations from normal potassium levels carry increased risk of mortality. Patiromer is approved for treatment of HK and has been shown in clinical trials to reduce serum potassium among patients with HK and comorbid conditions. Areas covered: We review pooled data from two clinical trials of patiromer in patients with CKD and HK, safety of patiromer in special populations, dru...
The term “therapeutic patient education” (TPE) refers to teaching by healthcare practicioners that is designed to help patients and families manage chronic disease and improve quality of life. TPE improves treatment adherance, reduces complications, reduces overall cost of care and improves survival in c ongestive heart failure, diabetes mellitus and rheumatoid arthritis, among other diseases. Stalder et al and other groups have described implementation of TPE for atopic dermatitis (AD). Widespread implementation of TPE programs for AD has been limited by issues of cost, limited time during a clinic visit, and ...
A 92-year-old Caucasian female with a history of hypertension and congestive heart failure presented with an erythematous and scaling plaque that enlarged over 15 years. While not painful, the plaque itched. Topical moisturizing creams and antifungals did not improve the lesion. Physical examination revealed a 27.0 x 16.0 cm suprapubic lesion, extending superiorly onto the abdomen, and inferiorly onto the right thigh. There was a 12.0 cm central macerated area. In other areas, there was hyperpigmentation.
Telemedicine and e-Health, Ahead of Print.
Galectin-3 (Gal-3) is increased in heart failure (HF) and promotes cardiac fibrosis and inflammation. We investigated whether Gal-3 modulates oxidative stress in human cardiac fibroblasts, in experimental animal models and in human aortic stenosis (AS). Using proteomics and immunodetection approaches, we have identified that Gal-3 down-regulated the anti-oxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. In parallel, Gal-3 increased peroxide, nitrotyrosine, malondialdehyde and N-carboxymethyl-lysine levels and decreased total antioxidant capacity. Gal-3 decreased prohibitin-2 expression without modifying other mitocho...
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Changes in QRS duration and pattern are regarded to reflect severe ischemia in acute coronary syndromes (ACS), and ventricular conduction blocks (VCBs) are recognized high-risk markers in both ACS and acute heart failure. Our aim was to evaluate the prevalence, temporal evolution, association with clinical and angiographic parameters, and impact on 1-year mortality of VCBs in ACS-related CS. Data of 199 patients with ACS-related CS from a prospective multinational cohort was evaluated with 12-lead ECG data from baseline and day 3.