Daylight Saving Time Starts Today. Here ’s What Losing An Hour of Sleep Really Does to Your Body
The start of Daylight Saving Time, when the clocks spring forward by an hour, is among the most hated days of the year. Aside from the obvious reason — losing an hour of sleep — research has shown that the time change, which this year falls on March 11, may contribute to everything from lost productivity to a heightened risk of heart attack and stroke. How can resetting your clocks do all that? TIME asked Dr. Cathy Goldstein, an assistant professor of neurology at the University of Michigan School of Medicine Sleep Disorders Center, what really happens to your body when you lose an hour of sleep for Daylight Saving Time. Your circadian rhythm is thrown off Daylight Saving Time’s true impact goes beyond losing an hour of sleep, Goldstein says. Your circadian rhythm, an internal clock that “exists so that wakefulness is promoted during the day, and sleep is promoted at night,” Goldstein says, is also affected. Thanks to circadian rhythms, the body begins secreting melatonin, a sleep-promoting hormone, around 9 p.m., with levels dropping way off by the next morning. Light exposure can moderate your circadian rhythm a bit, but the body more or less relies on consistent sleep and wakefulness cues — so when they’re altered, even by an hour, your sleep gets misaligned. “You take somebody who’s very sleepy when they get up at 6 a.m., and then they get up at 6 a.m. during Daylight Saving Time, and for them that’s physiologic...
Conclusions: Our report is the first study to examine the distant metastatic breast cancer proteome using FFPE tissues. The depth of our dataset allowed us to discover a novel biomarker candidate and a proteomic characteristics of distant metastatic breast cancer. Distinct molecular features of various breast cancer subtypes were also established. Our proteomic data constitute a valuable resource for research on distant metastatic breast cancer. PMID: 32489334 [PubMed]
Publication date: September 2020Source: Research in Developmental Disabilities, Volume 104Author(s): Kate Gwilliam, Anna Joyce, Dagmara Dimitriou
Conclusions: The results of the study show that the size of the scar can depend on the incision technique used. Larger scars after laser therapy limit the lymphatic flow of the skin, which may have an adverse effect on mapping sentinel lymph nodes. However, this hypothesis requires further research. PMID: 32489365 [PubMed]
Authors: Pala P, Bergler-Czop BS, Gwiżdż JM Abstract Telemedicine may be described as a modern technology supporting health care at a distance. Dermatology, as a visually-dependent specialty, is particularly suited for this kind of the health care model. This has been proven in a number of recent studies, which emphasized feasibility and reliability of teledermatology. Many patients in the world still do not have access to appropriate dermatological care, while skin cancers morbidity is on an upward trend. Technological development has enabled clinicians to care for diverse patient populations in need of skin exp...
Publication date: Available online 3 June 2020Source: CellAuthor(s): David Y. Oh, Serena S. Kwek, Siddharth S. Raju, Tony Li, Elizabeth McCarthy, Eric Chow, Dvir Aran, Arielle Ilano, Chien-Chun Steven Pai, Chiara Rancan, Kathryn Allaire, Arun Burra, Yang Sun, Matthew H. Spitzer, Serghei Mangul, Sima Porten, Maxwell V. Meng, Terence W. Friedlander, Chun Jimmie Ye, Lawrence Fong
Publication date: Available online 4 June 2020Source: Obesity Research &Clinical PracticeAuthor(s): Diego Moriconi, Stefano Masi, Eleni Rebelos, Agostino Virdis, Maria Laura Manca, Salvatore De Marco, Stefano Taddei, Monica Nannipieri
Publication date: Available online 3 June 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Maciej Roman, Tomasz P. Wrobel, Agnieszka Panek, Czeslawa Paluszkiewicz, Wojciech M. Kwiatek
Conclusions: Our work demonstrates the current developments of a novel endoimaging system equipped with the potential to generate 3D bladder reconstructions from cystoscopy videos and AI-assisted automated detection of bladder tumors. PMID: 32491933 [PubMed - as supplied by publisher]
CONCLUSION: Utilizing a large North American DTC registry, we found the prevalence of de novo TgAb detection to be 5% among initially TgAb negative patients. We did not find a statistically significant association between de novo TgAb development and DTC structural recurrence. Larger prospective studies are required to confirm these findings and further assess the significance of de novo TgAb detection in the follow up of DTC. PMID: 32484055 [PubMed - as supplied by publisher]
"A Prospective Mixed-Methods Study of Decision-Making on Surgery or Active Surveillance for Low-Risk Papillary Thyroid Cancer" by Sawka AM et al. (Thyroid 2020 Apr 8. doi: 10.1089/thy.2019.0592. Online ahead of print). Thyroid. 2020 Jun 02;: Authors: Miyauchi A, Ito Y, Davies L Abstract The aforementioned article was published online (ahead of print) recently in Thyroid. Sawka AM et al. prospectively used standardized medical information to offer a choice between active surveillance (AS) and surgery to eligible patients at their practice in Toronto, Canada, and reported their experiences usin...