MiR-145 improves macrophage-mediated inflammation through targeting Arf6

ConclusionsBy means of reducing the expression of Arf6 and subsequent signal transduction via NF-kappaB, miR-145 plays a role in inhibiting the secretion of inflammatory factors and then improving the inflammatory status. MiR-145 might be one of the candidates for anti-inflammatory treatment for metabolic diseases.
Source: Endocrine - Category: Endocrinology Source Type: research