Body language: UCLA's surgical residents sharpen their skills in special lab

Under the glare of operating-room lights, six UCLA neurosurgery residents embarked on a rare adventure into the human body. As they started cutting into three bodies, Dr. Warwick Peacock, professor of surgery, encouraged them onward. “That should be the linea alba,” he said in his gentle South African accent. “There are some adhesions. Always stick your finger in to make sure you’re not cutting into the bowel. It spoils the day.” Incisions made, the residents approached the spine from the front, sawing through the sternum, moving beyond the lungs and following the rib head to the pedicle, then removing a thoracic disc on each body — in two hours. Completing a discectomy in two hours on a living patient would be extraordinary. But this was no OR. The bodies are cadavers, and the bitter and antiseptic scent of embalming fluid, not blood, fills the air. In UCLA’s Surgical Science Laboratory — one of the few of its kind dedicated to the training of surgical residents — the fledgling surgeons can practice and make mistakes. They bubble with excitement, viewing anatomy rarely seen in this era of minimally invasive surgery and computer modeling: lungs, the front of the spine, the aorta. For Dr. Peacock, an emeritus pediatric neurosurgeon — who developed new techniques for treating children with cerebral palsy by first trying these techniques out on cadavers — teaching residents and exploring the human body on a daily ...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

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We report a case of a patient transplanted 13  years ago for NET metastases, with a lesion histologically proved for NET metastasis located at the cava vein anastomosis. He was treated with percutaneous radiofrequency ablation (RFA) after a first failed attempt of endovascular approach. The vascular heat sink, which RFA is susceptible to, was considered an advantage in this case, since it restricted the propagation of heat only to the tissue located in the very proximity of the RFA antenna, protecting the inferior vena cava vessel walls. This positive result may suggest an additional use of RFA in selected challenging cases.
Source: CardioVascular and Interventional Radiology - Category: Radiology Source Type: research
Conclusion: Increased HMP pressure improves graft perfusion but does not affect DGF incidence or 1-year graft survival. PMID: 30425194 [PubMed - in process]
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
Abstract Background: Hypothermic machine perfusion (HMP) is being used more often in cardiac death kidney transplantation; however, the significance of assessing organ quality and predicting delayed graft function (DGF) by HMP parameters is still controversial. Therefore, we used a readily available HMP variable to design a scoring model that can identify the highest risk of DGF and provide the guidance and advice for organ allocation and DCD kidney assessment. Methods: From September 1, 2012 to August 31, 2016, 366 qualified kidneys were randomly assigned to the development and validation cohorts in a 2:1 di...
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
Publication date: Available online 14 November 2018Source: Journal of Clinical Orthopaedics and TraumaAuthor(s): Raju Vaishya, Ankur Kansagra, Vipul Vijay, Abhishek Vaish, Amit Kumar AgarwalAbstractOsteochondritis dissecans (OCD) of the knee joint affects subchondral bone first, and then it involves the articular cartilage. It can cause pain, effusion and loose body formation. Nonoperative treatment is for the stable lesion, but if the lesion is unstable and symptomatic, then operative management is needed. Short term goal of the treatment is pain relief, and the long-term goal is the prevention of early arthritis. Surgica...
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
A nurse's decision to donate a kidney to a patient triggered a series of events that led to three people getting new organs at two Kansas City-area hospitals
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Cam Underwood, the son of a California pastor, underwent the complicated surgery.
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
CONCLUSION: We conclude that miR-146a-5p expression has a distinct pattern in the renal tissue and perhaps in the peripheral blood in the setting of DGF. Further refinements and strategies for studies should be developed in the field of non-invasive molecular diagnosis of kidney graft dysfunction. PMID: 30421783 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Authors: Cambruzzi E, Pêgas KL Abstract Lipoprotein glomerulopathy (LPG) is an uncommon cause of nephrotic syndrome and/or kidney failure. At microscopy, LPG is characterized by the presence of lipoprotein thrombi in dilated glomerular capillaries due to different ApoE mutations. ApoE gene is located on chromosome 19q13.2, and can be identified in almost all serum lipoproteins. ApoE works as a protective factor in atherosclerosis due its interaction with receptor-mediated lipoprotein clearance and cholesterol receptor. Most common polymorphisms include ApoE2/2, ApoE3/2, ApoE3/3, ApoE4/2, ApoE4/3, and ApoE4/4....
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
With the proposed changes to the Affordable Care Act (ACA), 20 million Americans are at risk of losing their health care coverage. A survey, conducted by Brunswick Partners, found that “75 percent of Americans agree that the proposed changes to Medicaid in the AHCA are a bad idea. And that we should not allow 14 million Americans to become uninsured even if there is a potential to reduce Medicaid spending. These results are significant because they find majorities of Americans identifying as conservatives (55 percent), moderates (82 percent) and liberals (90 percent) are opposed to the AHCA’s Medicaid pro...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Conclusion: The use of human embryonic stem cell therapy may be a safe and effective treatment for patients with autism spectrum disorder. Studies with larger sample sizes are needed to support the use of human embryonic stem cell therapy in this patient population. Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social disconnection, incomplete verbal and nonverbal communication, severely restricted interests, and display of stereotyped and repetitive obsessive behaviors.[1,2] The current diagnosis of ASD is based on the revised criteria in the fifth edition of the Diagnostic ...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Autism Behavioral and Cognitive Neurology Case Review Current Issue Neurologic Systems and Symptoms Pervasive Developmental Disorders brain related disorder hESC human embryonic stem cell neurodevelopmental disorder stem cell therapy Source Type: research
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