Targeting Antibiotic Tolerance, Pathogen by Pathogen

We describe how these insights are leading to the development of species-specific therapeutic strategies for targeting antibiotic tolerance and highlight experimental platforms that are enabling us to better understand the complexities of drug-tolerant pathogens in in vivo settings. Teaser Lack of efficacy of antibiotic treatment presents a critical challenge to clinical management of bacterial infections. This review discusses the significance of antibiotic tolerance as the culprit of this challenge and its underlying mechanism as the target for future therapeutic development.
Source: Cell - Category: Cytology Source Type: research