Influence of inter-observer delineation variability on radiomics stability in different tumor sites.

CONCLUSION: Inter-observer delineation variability has a relevant influence on radiomics analysis and is strongly influenced by tumor type. This leads to a reduced number of suitable imaging features. PMID: 29513054 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research

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For 22 years, the world's largest pure-play medical device company was the only player in sacral neuromodulation, a space that addresses urinary problems as well as fecal incontinence. Now there's a new kid on the block, which has created quite an intense David vs. Goliath medtech story. For those unfamiliar with the Axonics vs. Medtronic story up to this point, click here for a quick rundown of recent events that have transpired in this market.   FDA Approves Second Indication for Axonics r-SNM FDA approved the urinary indications for an implantable rechargeable sacral neuro...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Implants Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
A Holyrood committee finds 18% of cancer patients in June were not seen within the six-week target.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
ConclusionsThe effect of therapy directed toward EGFR mutation or EML4 –ALK fusion gene might obscure the significant prognostic difference between M1b and M1c.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
ConclusionApalutamide had manageable safety profile, without any DLT or any new safety signals, and favourable efficacy in Japanese mCRPC patients. Thus, it was ascertained to be an adequate dosage regimen in Japanese mCRPC patients.Trial registrationClinicalTrials.gov identifier: NCT02162836.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
Attack on cancer drug comes amid near-halving in sector value since last year
Source: FT.com - Drugs and Healthcare - Category: Pharmaceuticals Source Type: news
Roche today announced that results from a number of studies from across its growing breast cancer portfolio will be presented at the San Antonio Breast Cancer Symposium (SABCS), from 10-14 December 2019.
Source: Roche Media News - Category: Pharmaceuticals Source Type: news
Publication date: Available online 16 November 2019Source: Materials Science and Engineering: AAuthor(s): Zeju Weng, Kaixuan Gu, Kaikai Wang, Xuanzhi Liu, Junjie WangAbstractDeep cryogenic treatment (DCT) is believed to have superior performance in coordination with traditional heat treatment. In present work, the effect of DCT combined with inter-critical quenching treatment on the mechanical properties and microstructure of 30CrMnSi alloy structural steel was investigated. Before DCT employed, quenching treatment was conducted at different austenitizing temperatures (780 °C, 820 °C and 900 °C) to obtain...
Source: Materials Science and Engineering: A - Category: Materials Science Source Type: research
Publication date: 1 February 2020Source: Materials Chemistry and Physics, Volume 241Author(s): Nicoleta Badea, Mariela Madalina Craciun, Andreea Sofia Dragomir, Mihaela Balas, Anca Dinischiotu, Claudiu Nistor, Camelia Gavan, Daniela IonitaAbstractThe paper is concerned with obtaining nanosystems based on multiwalled carbon nanotubes (MWCNT), pemetrexed (Pm) and quercetin (Q) with antitumor action. MWCNT were contacted with ethanolic solutions of Pm/Q/Pm-Q, centrifuged and then filtered. The obtained nanosystems were structurally characterizedcaracterized by FTIR analysis. The physical stability of the nanosystem was assess...
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research
Joe Abdo1, Christopher S. Wichman2, Nicholas E. Dietz1,3, Pawel Ciborowski4, John Fleegel1, Sumeet K. Mittal1,5 and Devendra K. Agrawal1* 1Department of Clinical and Translational Science, Creighton University School of Medicine, Omaha, NE, United States 2Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States 3Department of Pathology, CHI Health Creighton University Medical Center, College of Medicine, Omaha, NE, United States 4Department of Pharmacology, University of Nebraska Medical Center, Omaha, NE, United States 5Norton Thoracic Institute, St....
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
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