Tooth loss is associated with accelerated cognitive decline and volumetric brain differences: a population-based study

Tooth loss has been related to cognitive impairment, however its relation to structural brain differences in humans is unknown. Dementia-free participants (n= 2715) age ≥60 years were followed for up to 9 years. A sub-sample (n=394) underwent MRI at baseline. Information on tooth loss was collected at baseline and cognitive function was assessed using the Mini-Mental State Examination (MMSE) at baseline and at follow-ups. Data were analyzed using linear mixed-eff ects models and linear regression models.
Source: Neurobiology of Aging - Category: Neuroscience Authors: Source Type: research