Teriparatide treatment exerts differential effects on the central and peripheral skeleton: results from the MOAT study

ConclusionsTeriparatide exerts differential effects on the central and the peripheral skeleton. Central trabecular vBMD (L1 –L3) is improved, but there is a concomitant decrease in peripheral cortical vBMD and an increase in porosity. Overall, we did not observe a change in total body bone mineral. We acknowledge that our conclusions may be speculative and are constrained by the technical limitations of the imaging tec hniques used, the lack of a control group, and the small sample size studied.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research