Analysis of relapse post transplant in acute leukemia, a comparative on second allogeneic hematopoietic cell transplant and donor lymphocyte infusions

• In this cohort of AML and ALL patients, second Allo-HCT and DLI showed comparable results.• The time interval from Allo-HCT to relapse is a strong predictor of outcomes for DLI and Second Allo-HCT, a shorter time associated lower OS and DFS.• Within the DLI cohort, patients receiving TCD at Allo-HCT had higher OS, DFS and lower relapse incidence.

Source: Experimental Hematology - March 8, 2018 Category: Hematology Authors: Guillermo Ort í, Jaime Sanz, Irene García-Cadenas, Isabel Sánchez-Ortega, Laura Alonso, Maria José Jiménez, Luisa Sisinni, Carmen Azqueta, Olga Salamero, Isabel Badell, Christelle Ferra, Cristina Diaz de Heredia, Rocio Parody, Miguel Angel Sanz, Jorg Source Type: research