Repeated Ranibizumab Injections Safe in Diabetic Macular Edema Repeated Ranibizumab Injections Safe in Diabetic Macular Edema

In patients with diabetic macular edema, repeated ranibizumab injections are not associated with impaired macular perfusion and can be safely offered even to those with severe microangiopathy and advanced capillary dropout, researchers say.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news

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Reward circuitry in the brain plays a key role in weight regulation. We tested the effects of a plant-based meal on these brain regions.
Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Randomized Control Trials Source Type: research
Condition:   Metabolic Syndrome Interventions:   Drug: Liraglutide;   Other: Exercise training;   Drug: Liraglutide + Exercise training Sponsors:   University of Virginia;   National Institutes of Health (NIH);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: No significant differences were found in peripapillary and macular microcirculation detected by OCTA between AD and ED glaucomatous eyes. Peripapillary and macular microcirculation were significantly correlated with disease severity in AD and ED glaucomatous eyes.
Source: Journal of Glaucoma - Category: Opthalmology Tags: Original Studies Source Type: research
This study aims to evaluate the effect of conbercept with 3+ pro re nata (PRN) on macular perfusion status in patients with dia...
Source: BMC Ophthalmology - Category: Opthalmology Authors: Tags: Research article Source Type: research
ConclusionThe use of ICG to visualize tissue perfusion in low rectal resections for cancer can lead to a reduction of AL.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Purpose: The impact of peripheral retinal lesions (PL) visualized with ultra–wide-field imaging on diabetic retinopathy (DR) remains unclear. The purpose of this study was to assess the presence of PL and their association with macular microvasculopathy, metabolic dysfunction, and neurodegeneration in patients with Type II diabetes and early retinal disease. Methods: Forty-five degree color fundus (Topcon) and 200° ultra–wide-field images (Optos) were assessed for the presence and severity of DR. Lesions anterior to the 45° were considered peripheral. The foveal avascular zone area, perimeter and a...
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
CONCLUSION: Arterial spectral waveform features may be useful in predicting the chance of diabetic foot ulcer healing. PMID: 32957822 [PubMed - as supplied by publisher]
Source: Perfusion - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Perfusion Source Type: research
Authors: Wright WS, Eshaq RS, Lee M, Kaur G, Harris NR Abstract In this article, we present a discussion of diabetes and its complications, including the macrovascular and microvascular effects, with the latter of consequence to the retina. We will discuss the anatomy and physiology of the retina, including aspects of metabolism and mechanisms of oxygenation, with the latter accomplished via a combination of the retinal and choroidal blood circulations. Both of these vasculatures are altered in diabetes, with the retinal circulation intimately involved in the pathology of diabetic retinopathy. The later stages of d...
Source: Comprehensive Physiology - Category: Physiology Tags: Compr Physiol Source Type: research
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Source: Journal of Addictive Diseases - Category: Addiction Authors: Source Type: research
Abstract PURPOSE: To investigate and quantify peripapillary vascular and neuronal changes secondary to diabetic retinopathy, using spectral-domain optical coherence tomography (OCT) and OCT angiography (OCTA). DESIGN: This was a cross-sectional study. METHODS: 51 eyes of 51 patients affected by non-proliferative diabetic retinopathy (NPDR) and 19 age-matched healthy control eyes underwent full ophthalmic examination, including OCT and OCTA in the peripapillary area. Vessel area density (VAD), vessel length fraction (VLF) and vessel diameter index (VDI) were quantified in a ring-shaped region of interest ...
Source: The British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Br J Ophthalmol Source Type: research
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