Regulation of fluid reabsorption in rat or mouse proximal renal tubules by asymmetric dimethylarginine (ADMA) & dimethylarginine dimethylaminohydrolase (DDAH) 1.

CONCLUSIONS: Fluid reabsorption in the proximal tubule is reduced by tubular ADMA or by blocking its metabolism by DDAH-1. L-257 is a novel regulator of proximal tubule fluid reabsorption.
PMID: 29513072 [PubMed - as supplied by publisher]

Source: Am J Physiol Renal P... - March 7, 2018 Category: Urology & Nephrology Authors: Bell T, Araujo M, Luo Z, Tomlinson J, Leiper J, Welch WJ, Wilcox CS Tags: Am J Physiol Renal Physiol Source Type: research