Arthur Vick Prize 2017 of the German Society of Orthopaedic Rheumatology.

[Arthur Vick Prize 2017 of the German Society of Orthopaedic Rheumatology]. Z Rheumatol. 2018 Mar 05;: Authors: Bause L, Niemeier A, Krenn V Abstract The German Society of Orthopaedic Rheumatology (DGORh) honored Prof. Dr. med. Veit Krenn (MVZ-ZHZMD-Trier) with the Arthur Vick Prize 2017. With this award, scientific results with high impact on the diagnosis, therapy and pathogenetic understanding of rheumatic diseases are honored. In cooperation with pathologists and colleagues from various clinical disciplines Prof. Dr. med. Veit Krenn developed several histopathologic scoring systems which contribute to the diagnosis and pathogenetic understanding of degenerative and rheumatic diseases. These scores include the synovitis score, the meniscal degeneration score, the classification of periprosthetic tissues (SLIM classification), the arthrofibrosis score, the particle score and the CD15 focus score. Of highest relevance for orthopedic rheumatology is the synovitis score which is a semiquantitative score for evaluating immunological and inflammatory changes of synovitis in a graded manner. Based on this score, it is possible to divide results into low-grade synovitis and high-grade synovitis: a synovitis score of 1-4 is called low-grade synovitis and occurs for example in association with osteoarthritis (OA), post-trauma, with meniscal lesions and hemochromatosis. A synovitis score of 5-9 is called high-grade synovitis, e.g. rheumatoid ...
Source: Zeitschrift fur Rheumatologie - Category: Rheumatology Authors: Tags: Z Rheumatol Source Type: research

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Analyst, 2019, Accepted Manuscript DOI: 10.1039/C8AN02014K, PaperDehui Sun, Fanlei Hu, Huanyu Gao, Zhijing Song, Wenchun Xie, Ping Wang, Lianjie Shi, Ke Wang, Yan Li, Chuncui Huang, Zhanguo Li Glycosylation is a post-translational modification essential for maintaining the structure and function of proteins. Abnormal N-glycan patterns have been found in various diseases compared to healthy controls. Decrease in terminal... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Introduction: Despite the availability of multiple pharmaceutical and targeted biological drugs for treatment of rheumatoid arthritis (RA), many patients exhibit intolerability or inadequate clinical response. Modulating innate anti-inflammatory neuro-immune pathways through electrical stimulation of the vagus nerve may represent a novel, nonpharmacological means of treating RA and other immune-mediated inflammatory diseases. We recently reported a 12-week proof-of-concept study with an implanted neuromodulation device, showing reduction in the DAS28-CRP disease activity score, with concomitant reductions in TNF - α ...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
Vagal nerve stimulation is gaining recognition as an important therapeutic approach especially for non-communicable diseases such as cardiovascular disease (CVD), Depression, Fibromyalgia, Arthritis, Type 2 Diabetes, Alzheimer, and certain types of cancer. In turn, decreased vagal tone its implicated in the prognosis of a wide range of diseases. Afferent vagal stimulation seems to have the key to reset certain pathophysiological states of the body leading to health improvement by reshaping neural networks.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
The only doctor in B.C.’s Interior that cares for children with juvenile arthritis has just retired, with no replacement, leaving families concerned with how their children will get proper medical treatment.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/British Columbia Source Type: news
Conclusion: The proposed system is simple to use and convenient for use in ambulatory or unsupervised environments for joint measurement; however, it was shown that accuracy can be sensitive to sensor placement. Significance: This system would be beneficial for obtaining quantitative patient data or tracking functional activity in variable environments, providing clinicians with indications of how patients’ knees function during activity, potentially permitting more individualized care and recommendations.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Corrina Towers,  51, from Great Missenden, suffered relentless fatigue, osteoarthritis in both knees and endured almost constant abdominal bloating and discomfort.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ConclusionOur finite element model provides a realistic three-dimensional knee model to investigate the effects of degenerative and radial meniscal tears and resultant meniscectomy on the stress distribution of the knee. The stress was increased in meniscal tears and increased significantly when meniscectomy was performed. Increased meniscus extrusion may explain the mechanism for higher stress on the components of the knee.The translational potential of this articleMeniscal tears are the most common damage associated to the menisci, and meniscectomy is often performed to relieve the pain and instability of the knee. The r...
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research
ConclusionsA higher percentage of quadriceps muscle and better muscle quality (lower EI) was associated with better function. Age and exercise levels influenced function. Ultrasound may provide
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
Authors: Silverman ED Abstract The 72nd Annual Meeting of The Canadian Rheumatology Association (CRA) was held at The Westin Ottawa, Ottawa, Ontario, Canada, February 8-11, 2017. The program consisted of presentations covering original research, symposia, awards, and lectures. Highlights of the meeting include the following 2017 award winners: Dr. Vinod Chandran, Young Investigator; Dr. Jacques P. Brown, Distinguished Investigator; Dr. David Robinson, Teacher-Educator; Dr. Michel Zummer, Distinguished Rheumatologist; Ms. Rebecca Gole, Best Abstract on SLE Research by a Trainee - Ian Watson Award; Ms. Bailey Russell...
Source: Journal of Rheumatology - Category: Rheumatology Tags: J Rheumatol Source Type: research
[Fifteen years of the histopathological synovitis score : Review and further developments of a diagnostic score]. Z Rheumatol. 2017 May 03;: Authors: Krenn V, Perino G, Rüther W, Krenn VT, Huber M, Hügle T, Najm A, Müller S, Boettner F, Pessler F, Waldstein W, Kriegsmann J, Häupl T, Wienert S, Krukemeyer MG, Sesselmann S, Tikhilov R, Morawietz L Abstract The histopathological synovitis score evaluates in a graded approach, as is largely usual for diagnostic histopathological scores, the immunological and inflammatory changes caused by synovitis. A synovitis scor...
Source: Zeitschrift fur Rheumatologie - Category: Rheumatology Authors: Tags: Z Rheumatol Source Type: research
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