Association Between Marginal Jawbone Loss and Onset of Rheumatoid Arthritis and Relationship to Plasma Levels of RANKL

ConclusionMarginal jawbone loss preceded the clinical onset of RA symptoms, but this was observed only in nonsmokers. Moreover, marginal jawbone loss was significantly greater in RANKL‐positive presymptomatic subjects compared with RANKL‐negative presymptomatic subjects and was highest in presymptomatic subjects positive for both ACPA and RANKL.

Source: Arthritis and Rheumatism - March 7, 2018 Category: Rheumatology Authors: Elin Kindstedt, Linda Johansson, Py Palmqvist, Cecilia Koskinen Holm, Heidi Kokkonen, Ingegerd Johansson, Solbritt Rantap ää Dahlqvist, Pernilla Lundberg Tags: Original Article Source Type: research