Fundamental role of dendritic cells in inducing Th2 responses.

Fundamental role of dendritic cells in inducing Th2 responses.
Korean J Intern Med. 2018 Mar 05;:
Authors: Kim B, Kim TH
Abstract
A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper 1 (Th1) and Th17 responses, the mechanisms that initiate Th2 responses remain obscure. Antigen-presenting cells, particularly dendritic cells (DCs), are mandatory for the induction of a Th cell response. Numerous studies have documented the organizing role of DCs in this process. The present review summarizes the fundamental roles of DCs in inducing Th2 responses.
PMID: 29502361 [PubMed - as supplied by publisher]

Source: The Korean Journal of Internal Medicine - March 5, 2018 Category: Internal Medicine Authors: Kim B, Kim TH Tags: Korean J Intern Med Source Type: research