OraCoat ® XyliMelts® Combat Tooth Erosion by Reducing Gastroesophageal Reflux Disease (GERD)

A Recent Study Shows that Nightly Use of Oral Adhering Discs Significantly Improves Symptoms Associated with GERDSeattle, WA (February 21, 2018) –An article about a recent clinical study, “Dental Erosion, GERD, and Salivary Stimulation,” published in theJournal of Oral&Dental Health, February2018, reports that OraCoat® XyliMelts® oral adhering discs used while sleeping reduce reflux of stomach acids, in gastroesophageal reflux disease (GERD), which causes tooth erosion. In patients with GERD, the esophagus is exposed to stomach acid long enough to cause symptoms.GERD is estimated to occur in ten to thirty percent of the population in developed countries and is known to contribute to or cause a number of medical and dental problems including heartburn (chest pain), sore throat, mucosal pathology, bruxism,and tooth erosion. The condition is also associated with sleep disturbance and can have a detrimental effect on nighttime comfort and overall quality of life. Saliva is believed to play an integral role in combatting symptoms of GERD by protecting the esophageal lining by way of diluting and neutralizing stomach acid that enters the esophagus through reflux. However, saliva production normally decreases at night and, when the body is prone, gravity no longer helps to keep the acid down.The study was conducted as a randomized, double-blind, controlled trial involving twoover-the-counter products currently on the market for use in the management of ...
Source: Dental Technology Blog - Category: Dentistry Source Type: news

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Authors: Voitey M, Bouiller K, Chirouze C, Fournier D, Bozon F, Klopfenstein T Abstract INTRODUCTION: Little is known about the functional symptoms associated with Lyme borreliosis (LB) in Europe. We aimed to assess functional symptoms associated with presumed LB and to compare patients with and without confirmed LB. MATERIALS AND METHODS: We performed a retrospective monocenter study. Patients consulting for presumed LB were included. RESULTS: Between November 2015 and June 2018, 355patients were included (mean age: 51years, 52% of women) of which 48had LB: erythema migrans (42%), early disseminated LB (50...
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
Publication date: Available online 15 November 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Amanda D'Espessailles, Natalia Santillana, Sofía Sanhueza, Cecilia Fuentes, Mariana CifuentesAbstractExcess adipose tissue (AT) associates with inflammation and obesity-related diseases. We studied whether calcium-sensing receptor (CaSR)-mediated NLRP3 inflammasome activation in THP-1 macrophages elevates inflammation in LS14 preadipocytes, modeling deleterious AT cell crosstalk. THP-1 macrophages exposed to Cinacalcet (CaSR activator, 2 μM, 4 h) showed elevated proinflammatory marker and NLRP3 inflammaso...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Publication date: Available online 14 November 2019Source: Pharmacological ResearchAuthor(s): Lijuan Wu, Fei Li, Changying Zhao, Yao Ming, Chunmei Zheng, Yonglin Li, Shihang Lei, Chen ChenAbstractThe incidence of ischemic cardiomyopathy (ICM) is increasing yearly, which seriously endangers human health. There is rarely any remarkable progress in the treatment of ICM from the available drugs. Recent research shows that natural herbal medicine may have beneficial effects in the prevention and treatment of cardiovascular diseases. The effective extracts of the herbs may improve myocardial ischemia through various actions, suc...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
ConclusionThese results indicate that A. farnesiana pods contain nematocidal compounds and might be promising natural anthelmintic agents against H. contortus. This leguminous plant could be used as a nutraceutical food source for the control of gastrointestinal nematodes in small ruminants.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionsWe found that EFVF is safe with regard to acute toxicity in rats as well as genotoxicity such as mutagenesis or clastogenesis under the present experimental conditions. These results might support the safety of EFVF as a potential therapeutic material for the traditional use or pharmaceutical development.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
D. Zhang, D. Chen, Shengsuo Ma, Wenyan Bian, F. Xie, Meina Huang, Haoming Lin, Qianxing Zhan and G. Zhao*
Source: Indian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research
Authors: Hay ME, Connelly DM Abstract Physical inactivity and chronic back pain are prevalent among older adults; however, there are individuals who persist in exercising despite daily pain. This research explored the meaning of exercise in the lives of older adults with chronic back pain. Hermeneutic phenomenology, valuing everyday experiences and highlighting meaning, was employed. Individual in-depth interviews with 10 adults aged 65 years and older gathered rich descriptions of their experiences. Data collection and analyses were iterative processes. The experience of exercise was inextricably connected with ol...
Source: Journal of Aging and Physical Activity - Category: Geriatrics Tags: J Aging Phys Act Source Type: research
This study aimed to determine the feasibility of an occupational therapy intervention to address sedentary behavior and pain among older adults residing in assisted living facilities. A single group pretest and posttest design was implemented using the Sedentary Behavior Questionnaire, actigraphy technology, and daily activity logs to measure sedentary behavior. The Short-Form McGill Pain Questionnaire was used to assess pain. Occupational therapy intervention focused on individualized goals related to participation in meaningful physical activities, which were established in collaboration with the participant and were tra...
Source: Journal of Aging and Physical Activity - Category: Geriatrics Tags: J Aging Phys Act Source Type: research
This study included 24 patients (18 females) with a median age of 51.5 years (range, 21-68 years). Ten cases were symptomatic and 14 were asymptomatic. Cysts were retrorectal in 21 patients. Cysts were below the coccyx level in 16 patients, opposite the coccyx in 6, and above the coccyx in 2. Cysts were supralevator in 5 patients, had a supra- and infralevator extension in 18 patients, and were infralevator in 1. Ten patients were managed using an anterior laparoscopic approach, 11 using a posterior approach, and 3 using a combined approach. Mean cyst size was 5.5 ± 2.7 cm. Postoperative complications were Clavien-D...
Source: Annals of Coloproctology - Category: Gastroenterology Tags: Ann Coloproctol Source Type: research
CONCLUSION: Men with rectal prolapse were younger, healthier, and had relatively better anorectal function than women. The Delorme-Thiersch operation in men promoted lower recurrence rates and was advantageous in preserving the fertility of young patients, but the incidence of complications was also higher in men. Adequate counseling and preparation for the possibility of complications are needed. PMID: 31726002 [PubMed]
Source: Annals of Coloproctology - Category: Gastroenterology Tags: Ann Coloproctol Source Type: research
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