Effect of nutrient deprivation on the expression and the epigenetic signature of sirtuin genes

Conclusions Epigenetic mechanisms may have a role in the sirtuin response to nutrient deprivations in cultured hepatoma cells. Replicating these results in vivo to achieve a comprehensive understanding of the epigenetic control of sirtuin expression following nutrient deprivations might open up novel therapeutic possibilities to cure metabolic diseases and promote human health.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research