A novel Hemi-Body Irradiation technique using electron beams (HBIe −)

Certain radiation responsive skin diseases, such as Kaposi ’s sarcoma (KS), mycosis fungoides (MF) and Sézary syndrome (SS), may develop symptoms on the upper or the lower half of the body. KS, in its epidemic form, is frequently present in patients with a prior infection of HIV-1 retrovirus [1–3]. Most common irradiation techniques for KS either invol ve schemes of 20 Gy in 5 fractions or 24 Gy in 12 fractions [4–7], producing similar responses and toxicities. For small areas of occurrence, treatment of the superficial targets can be performed with X-rays using VMAT techniques [1] or via brachytherapy using surface applicators [8], while fo r large areas, electron beams are preferable due to the short range of electrons which produces less total body dose.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research