Systematic review: adrenal insufficiency secondary to swallowed topical corticosteroids in eosinophilic oesophagitis

ConclusionTopical corticosteroids were associated with adrenal insufficiency in a minority of patients. Most cases came from uncontrolled observational studies, with widely varying definitions of adrenal insufficiency. Longer follow‐up and larger controlled studies are needed to quantify the risk of adrenal insufficiency with maintenance topical corticosteroid therapy in EoE.

Source: Alimentary Pharmacology and Therapeutics - March 5, 2018 Category: Drugs & Pharmacology Authors: H. Philpott, M. K. Dougherty, C. C. Reed, M. Caldwell, D. Kirk, D. J. Torpy, E. S. Dellon Tags: SYSTEMATIC REVIEW Source Type: research