Cerebral microhemorrhages due to traumatic brain injury and their effects upon the aging human brain

Although cerebral microbleeds (CMBs) are frequently associated with traumatic brain injury (TBI), their effects upon clinical outcome after TBI remain controversial and poorly-understood, particularly in older adults. Here we (A) highlight major challenges and opportunities associated with studying the effects of TBI-mediated CMBs, (B) review the evidence on their potential effects upon cognitive and neural outcome as a function of age at injury, and (C) suggest priorities for future research on understanding the clinical implications of CMBs.

Source: Neurobiology of Aging - March 5, 2018 Category: Neuroscience Authors: Andrei Irimia, John D. Van Horn, Paul M. Vespa Source Type: research