Broadly neutralizing antibody treatment may target viral reservoir in monkeys

(NIH/National Institute of Allergy and Infectious Diseases) After receiving a course of antiretroviral therapy for their HIV-like infection, approximately half of a group of monkeys infused with a broadly neutralizing antibody to HIV combined with an immune stimulatory compound suppressed the virus for six months without additional treatment, according to NIAID-supported scientists. The therapy may have targeted the viral reservoir -- populations of long-lived, latently infected cells that harbor the virus and that lead to resurgent viral replication when suppressive therapy is discontinued.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news