What are Indications for Allergen-specific Immunotherapy?

Discussion Allergen-specific immunotherapy (AIT) is a disease modifying treatment for allergic disease. Sometimes referred to as desensitization, the premise is to expose the patient to small but regular amounts of a specific antigen thereby building tolerance within the patient to the allergen. AIT is often underused because of safety concerns and lack of appropriately trained health care providers and facilities to safely carry out AIT treatment. There are 4 main AIT treatments options currently: SCIT – subcutaneous immunotherapy Allergen is injected into the subcutaneous skin “Shots are effective in treating reactions to many allergens, including trees, grass, weeds, mold, house dust, dander, and insect stings.” SCIT is safe when used for selected individuals and given by trained health care providers in a setting that has immediate access to treatment for anaphylaxis and resuscitation. Reactions are infrequent and usually localized with erythema or hives. Rarely anaphylaxis can occur. Patients with concomitant asthma have an increased risk of severe bronchospasm. Patients should also not exercise for 2 hours before or after injection. SLIT – sublingual immunotherapy Allergen drops or tablets are placed and held under the tongue for several minutes and then swallowed. Used for food allergies such as peanut allergy. Ragweed and pollen tablets and drops used in other countries. In the US tablets for grass, ragweed and house dust mite are available....
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news

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