Visualising plastic changes to the brain

(Ruhr-University Bochum) Tinnitus, migraine, depression, Alzheimer's: all these are examples of diseases with neurological causes, the treatment and study of which is more and more frequently being carried out by means of magnetic stimulation of the brain. However, the method's precise mechanisms of action have not, as yet, been fully understood. The work group headed by Dr Dirk Jancke from the Institut für Neuroinformatik was the first to succeed in illustrating the neuronal effects of this treatment method with high-res images.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

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ConclusionIn carotid artery dissections, prodromal symptoms such as transient ischemic attack, like in our patient, are rarely present in children. For good long term outcomes, it is very important to suspect, diagnose and initiate appropriate treatment in a rapid manner in carotid artery dissection before severe neurological findings such as acute ischemic stroke develops.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
This study examined the prevalence and associated factors of risky sexual behaviours among 1648 school-going adolescents using the 2012 Ghana Global School-based Student Health Survey. Our findings showed 33.5% of the participants had ever had sex 32.5% had multiple sexual partners and only 26.2% reported using condom during their last sexual intercourse. Being male, older age, anxiety, loneliness, suicidal ideation, being bullied, food insecurity (hunger), current alcohol and marijuana use were significant risk factors for being sexually experienced, multiple partners, but not condom use. Parental knowledge of activity wa...
Source: Journal of Adolescence - Category: Child Development Source Type: research
Publication date: Available online 21 July 2018Source: Chemico-Biological InteractionsAuthor(s): Bharath Kumar VelmuruganAbstractThe psychoactive properties of cannabinoids are well known and there has been a continuous controversy regarding the usage of these compounds for therapeutic purposes all over the world. Their use for medical and research purposes are restricted in various countries. However, their utility as medications should not be overshadowed by their negative physiological activities. This review article is focused on the therapeutic potential and applications of phytocannabinoids and endocannabinoids. It h...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Publication date: Available online 21 July 2018Source: Alzheimer's &DementiaAuthor(s):
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Publication date: Available online 21 July 2018Source: Journal of Psychiatric ResearchAuthor(s): Julie-Anne Tanner, Paige E. Davies, Nicholas C. Voudouris, Anashe Shahmirian, Deanna Herbert, Nicole Braganza, Ana Gugila, Bryan M. Dechairo, James L. KennedyAbstractFailed medication trials are common in the treatment of major depressive disorder (MDD); however, the use of combinatorial pharmacogenomics to guide medication selection has been previously associated with improved outcomes in the psychiatric care setting. The utility of combinatorial pharmacogenomics in patients with MDD in primary care and psychiatric care settin...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
ConclusionsACEs have a direct and indirect, via depression, negative effect on how adult individuals perceive other people's attitude towards themselves. Additionally, negative AoO mediates the effects of ACEs on depression. Childhood EmoNeg associates specifically with negative AoO and DEPS in adulthood.
Source: European Psychiatry - Category: Psychiatry Source Type: research
This study aimed to investigate the activity of RIP II in a corticosterone-induced depression mice model. Corticosterone (20 mg/kg, s.c.) was administered once a day for 21 days. RIP II (50 mg/kg, p.o.) or fluvoxamine (FLU, 50 mg/kg, standard antidepressant, p.o.) was administered after corticosterone (CORT) injection, for the last 7 days of CORT treatment. Mice were exposed to the following behavioral tests: forced swimming, tail suspension, open field, sucrose preference, elevated plus maze and ymaze. After behavioral evaluation, brain areas (prefrontal cortex, hippocampus and striatum) were dissected for neurochem...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
Publication date: Available online 21 July 2018Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Tong-Xian Zhang, Hua-Ji Liu, Yu ChenAbstractPhotoluminescent nanomaterials with a high quantum yield (QY) is preferred in many applications. Up to the present date, only a few organo-soluble Au-Ag bimetallic nanoclusters (NCs) have ever reported to exhibit a QY of more than 20%. Herein, ultrabright Au-Ag NCs with a maximum QY of ca. 23.6 % were synthesized with the assistance of mercaptosuccinic acid (MSA) and poly(N-vinylimidazole) (PVIm) through a two-step green route, which was almost two-fol...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
This study supports the view that burnout is associated with a depressive cognitive style.
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
ConclusionsWhile HRQoL at population level is most affected by balance problems, spasticity, and depression in RRMS, the biggest HRQoL losses in PMS are caused by spasticity, paralysis, weakness, and pain. Many symptoms with the largest effects in individuals substantially contribute to the population disease burden.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
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