Visualising plastic changes to the brain
(Ruhr-University Bochum) Tinnitus, migraine, depression, Alzheimer's: all these are examples of diseases with neurological causes, the treatment and study of which is more and more frequently being carried out by means of magnetic stimulation of the brain. However, the method's precise mechanisms of action have not, as yet, been fully understood. The work group headed by Dr Dirk Jancke from the Institut für Neuroinformatik was the first to succeed in illustrating the neuronal effects of this treatment method with high-res images.
CONCLUSIONS: The prevalence and incidence of dementia increase exponentially from the age of 65 onwards. As a consequence of the progressive ageing of the population and the increase in life expectancy, the number of cases of dementia will rise in the coming decades. Recent studies point to a slight drop in the accumulated risk of dementia adjusted by age groups and sex over the last few decades in some countries. It is possible that by means of primary prevention strategies implemented upon the known risk factors for dementia the burden of dementia on public health will diminish in the future. PMID: 29790571 [PubMed - in process]
CONCLUSIONS: Although the typical clinical manifestations of giant cell arteritis are headache, jaw claudication, loss of sight, constitutional symptoms and polymyalgia rheumatica, its presence must be suspected in patients over the age of 50 who manifest alterations affecting the peripheral nerve, including brachial diplegia with no other demonstrable cause. PMID: 29790570 [PubMed - in process]
CONCLUSION: Treatment with ESL could improve some aspects of theory of mind in patients with epilepsy, especially in men and independently of the control of seizures, with no changes in quality of life, anxiety or depression. PMID: 29790568 [PubMed - in process]
HIGH blood pressure symptoms include headaches, chest pain and difficulty breathing. But, adding apples to your diet could lower your risk of hypertension, a nutritionist has claimed. How many should you be eating to prevent the condition?
Conclusions: Perimenopausal HIV-infected women experienced a disproportionately high level of affective symptom burden over a 12-month observation period. Given the potential for these factors to influence adherence to HIV clinical care and quality of life, careful assessment and referral for treatment of these symptoms is essential.
After a series of high-profile drug failures, researchers are being forced to question their primary hypothesis of Alzheimer's disease.
(Kaiser Permanente) Combining data from electronic health records with results from standardized depression questionnaires better predicts suicide risk in the 90 days following either mental health specialty or primary care outpatient visits, reports a team from the Mental Health Research Network, led by Kaiser Permanente research scientists.
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Eponyms can be confusing and open to misinterpretation. By plotting the historical course of their folksonomic semantic derivation we gain a deeper understanding of the condition, the authors and the eponym. We review the early development of arrhythmia recording and the contributions of Luciani, Galabin, Gaskell, Wenckebachh, Hay and Mobitz to the current terminology associated with the categorization of Second-degree Atrioventricular block Current terminology Mob...
CONCLUSION: screening for anxiety and depression in adult cancer patients should form part of an early nursing assessment to identify those who may benefit from more structured interventions. HADS is a useful screening tool; however, further research is required on validating tools used to screen for anxiety and depression in cancer and chronic disease in different cultures to ensure validity and reliability of outcome data. PMID: 29791230 [PubMed - in process]
Conclusion Deficits in mitochondrial function, dynamics, and antioxidant capabilities putatively mediated through sub-optimal AMPK/SIRT/PGC-1α signaling, are involved in the development of early sub-clinical neurodegeneration in the cortex under diabetic conditions.