AHRA hosts clinical decision-support summit

The AHRA hosted a summit on February 20 to discuss the development of recommendations...Read more on AuntMinnie.comRelated Reading: AHRA, Canon award grants for patient initiatives Toshiba, AHRA open Putting Patients First grant program AHRA: Building a better breast cancer screening program AHRA: 6 ways to prepare for a Joint Commission visit AHRA, Toshiba open Putting Patients First grant program
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Authors: Guadagno E, De Rosa G, Nappi O Abstract A national project for the quality assessment of breast immunohistochemistry, involving 155 pathology laboratories distributed all over the Italian territory ( 19 regions), was carried out. The Project lasted one year from December 2014 to December 2015 and it was strongly supported by the Italian Society of Anatomic Pathology (SIAPEC/IAP). Proficiency tests were carried out by the Nordic Immunohistochemical Quality Control (NordiQC) organization. The main aim of the project was to investigate on the general performance of immunohistochemistry (ER, PR and HER2) in th...
Source: Pathologica - Category: Pathology Tags: Pathologica Source Type: research
ConclusionIn this nationwide study, multiple sclerosis patients did not have increased cancer incidence or increased cancer-specific mortality. We observed an increased risk of malignant melanoma mainly attributed to increased risk in the first part of our study period.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
This study aimed to analyze the association of CDH1 and TERT single-nucleotide polymorphisms with susceptibility to familial BC (FBC) risk in the Iranian patients. One hundred five patients with FBC and 110 non-FBC (NFBC) were genotyped to elucidate the potential association between CDH1 rs5030625 polymorphism and TERT rs2736098 polymorphism by polymerase chain reaction-restriction fragment length polymorphism. Then, results were evaluated by electrophoresis and Epi Info(™) 2012 software. A significant association was found between CDH1 rs5030625 GAGA genotype and FBC risk. Compared with the control group, the FBC pa...
Source: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy - Category: Microbiology Tags: Monoclon Antib Immunodiagn Immunother Source Type: research
Abstract OBJECTIVES: To compare the health-related quality of life (HRQOL) of women who did (receivers, n = 372) and did not (intentional nonreceivers, n = 46) receive all recommended adjuvant treatments for breast cancer. SAMPLE & SETTING: Women were recruited through integrative oncology clinics and the Cancer Surveillance System registry in western Washington. METHODS & VARIABLES: A cross-sectional and correlational study using secondary data was conducted. Self-reported data included involvement in treatment decision making (TDM) and HRQOL. Registry data included demographics, disease charact...
Source: Oncology Nursing Forum - Category: Nursing Authors: Tags: Oncol Nurs Forum Source Type: research
Abstract OBJECTIVES: To determine the incidence of financial toxicity among women with metastatic breast cancer, as well as the relationships among financial toxicity, quality of life, and overall cancer-related distress in members of this patient population. SAMPLE & SETTING: 145 women with metastatic breast cancer receiving care at an urban outpatient breast cancer clinic. METHODS & VARIABLES: A cross-sectional analysis of women with metastatic breast cancer was performed. Data were collected on patient characteristics, quality of life, cancer-related distress, and financial toxicity using self...
Source: Oncology Nursing Forum - Category: Nursing Authors: Tags: Oncol Nurs Forum Source Type: research
Authors: Qu N, Shi D, Shang M, Duan S, Guo L, Ning S, Li J Abstract BACKGROUND Ultrasound/microbubble (USMB)-mediated sonoporation is a new strategy with minimal procedural invasiveness for targeted and site-specific drug delivery to tumors. The purpose of this study was to explore the effect of different breast cancer cell lines on sonoporation efficiency, and then to identify an optimal combination of USMB parameters to maximize the sonoporation efficiency for each tumor cell line. MATERIAL AND METHODS Three drug-sensitive breast cell lines - MCF-7, MDA-MB-231, and MDA-MB-468 - and 1 multidrug resistance (MDR) ce...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Only 2 Weeks LeftWe wanted to get ourFBS in the hands of more cell culturing experts. Our low pricing has accelerated purchasing of this culture supplement.More importantly, we are pleased with the positive feedback. Here are some recentreviews.Linda S.on BirdEye  ★★★★★9 days agoMy experience with Neuromics was very positive. I asked for a sample of FBS and after to use the FBS I received. Peter T.on BirdEye ★★★★★month agoI purchased FBS from Neuromics. It was shipped to Canada without any problems. It arrived safely and still frozen. Cells grow well in the product. Customer ser...
Source: Neuromics - Category: Neuroscience Tags: FBS Fetal Bovine Serum Source Type: news
Abstract Recent remarkable advances in genome sequencing have enabled detailed maps of identified and interpreted genomic variation, dubbed "mutanomes." The availability of thousands of exome/genome sequencing data has prompted the emergence of new challenges in the identification of novel druggable targets and therapeutic strategies. Typically, mutanomes are viewed as one- or two-dimensional. The three-dimensional protein structural view of personal mutanomes sheds light on the functional consequences of clinically actionable mutations revealed in tumor diagnosis and followed up in personalized treatmen...
Source: Pharmacological Reviews - Category: Drugs & Pharmacology Authors: Tags: Pharmacol Rev Source Type: research
Publication date: February 2019Source: Phytochemistry Letters, Volume 29Author(s): Michael G. Knott, Jo-Anne de la Mare, Adrienne L. Edkins, Angel Zhang, Martin J. Stillman, John J. Bolton, Edith M. Antunes, Denzil R. BeukesAbstractThe endemic South African red seaweed Plocamium maxillosum (Poiret) Lamouroux produces two unusual isomeric dichlorinated cyclohexenone monoterpenes, plaxenone A and B (1 and 2). The structures of the isolated compounds were determined from spectroscopic data and their absolute configuration was determined by comparison of the experimental and calculated ECD spectra. Compounds 1 and 2 inhibit th...
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
Publication date: Available online 14 December 2018Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Qianqian Qian, Shiwei Niu, Gareth R. Williams, Jianrong Wu, Xueyi Zhang, Li-Min ZhuAbstractIn this work, we report K237-peptide functionalized chitosan (CS) nanoparticles (NPs) loaded with paclitaxel (PTX), for active targeting and effective treatment of KDR/Flk-1-overexpressing human breast cancer. The results displayed that the peptide-functionalized NPs put up favorable pH and temperature-sensitive characteristics. MTT assays showed that K237-CS (PTX)-g-PNIPAM NPs had a more peculiar and ...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
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