ASE releases updated guidelines for cardiac US agents

The American Society of Echocardiography (ASE) has published updated guidelines...Read more on AuntMinnie.comRelated Reading: ASE releases guide for imaging Chagas disease Medical societies celebrate ultrasound awareness Medical societies expand collaboration on cardiac registry ASE debuts new educational offerings ASE offers guide for childhood heart disease
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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CONCLUSIONS: Our data suggest no significant contribution of the analysed gene variants of cytokine-related molecules to development/severity of Chagas' heart disease, reinforcing the idea that parasite/host interplay is critical to CD outcomes. PMID: 29768622 [PubMed - in process]
Source: Memorias do Instituto Oswaldo Cruz - Category: Infectious Diseases Authors: Tags: Mem Inst Oswaldo Cruz Source Type: research
oz G, Apt W Abstract Chagas disease is a major public health problem in Latin America and has spread to other countries due to immigration of infected persons. 10-30% of patients with chronic Chagas disease will develop cardiomyopathy. Chagas cardiomyopathy is the worst form of the disease, due to its high morbidity and mortality. Because of its prognostic value and adequate medical monitoring, it is very important to identify infected people who could develop Chagas cardiomyopathy. The aim of this study was to determine if discrete typing units (DTUs) of Trypanosoma cruzi are related to the presence of heart dise...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
We have read with great interest the article by Bezerra et  al,1 in which an etiological classification of stroke in patients with Chagas heart disease using different systems is presented. By studying a tertiary referral center population composed of 32 patients with Chagas disease with stroke, the authors were able to show that although cardioembolic str oke affects the majority of patients, atherosclerosis and small-vessel occlusion still were important causes of stroke in patients with this condition.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research
The American Society of Echocardiography (ASE) has released a new guide for...Read more on AuntMinnie.comRelated Reading: Medical societies celebrate ultrasound awareness Medical societies expand collaboration on cardiac registry ASE: Echo protocol finds kids' heart abnormalities ASE debuts new educational offerings ASE offers guide for childhood heart disease
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
ConclusionsChD HF is an advanced form of HF with poor prognosis. Ivabradine was effective in reducing HR in these patients and improving functional class. Although our results are based on a very limited sample and should be interpreted with caution, they suggest that ivabradine may have a favourable benefit–risk profile in ChD HF patients.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
Publication date: Available online 4 October 2017 Source:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Author(s): Eugenia Pérez Caballero, Miguel H. Santamaría, Ricardo S. Corral Cardiac dysfunction with progressive inflammation and fibrosis is a hallmark of Chagas disease caused by persistent Trypanosoma cruzi infection. Osteopontin (OPN) is a pro-inflammatory cytokine that orchestrates mechanisms controlling cell recruitment and cardiac architecture. Our main goal was to study the role of endogenous OPN as a modulator of myocardial CCL5 chemokine and MMP-2 metalloproteinase, and its path...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
Chagas disease, caused by infection with the protozoan parasite Trypanosoma cruzi, is a leading cause of heart disease ("chagasic cardiomyopathy") in Latin America, disproportionately affecting people in resource-poor areas. The efficacy of currently approved pharmaceutical treatments is limited mainly to acute infection, and there are no effective treatments for the chronic phase of the disease. Preclinical models of Chagas disease have demonstrated that antigen-specific CD8+ gamma interferon (IFN-)-positive T-cell responses are essential for reducing parasite burdens, increasing survival, and decreasing cardiac...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Fungal and Parasitic Infections Source Type: research
ConclusionsAutonomic dysfunction may be responsible for additional morbidity in some infectious diseases.
Source: Clinical Autonomic Research - Category: Research Source Type: research
We have uncovered 80 medical files corresponding to original cases of Chagas' disease used for the classical description of the acute and cardiac forms of the disease. Sixty of them were diagnosed cardiac forms of the disease. The detailed clinical description of these 60 files are in excellent agreement with the nosography of progressive heart disease given by Chagas in his original 1922 paper. The reports we had access to, characterize a novel form of cardiac disease, dominated by progressive AV block, enlargement and displacement of the heart and sudden death, in relatively young adults including juveniles.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
We have uncovered 80 medical files corresponding to original cases of Chagas' disease used for the classical description of the acute and cardiac forms of the disease. Sixty of them were diagnosed cardiac forms of the disease. The detailed clinical description of these 60 files is in excellent agreement with the nosography of progressive heart disease given by Chagas in his original 1922 paper. The reports we had access to, characterize a novel form of cardiac disease, dominated by progressive AV block, enlargement and displacement of the heart and sudden death, in relatively young adults including juveniles.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
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