Frequency of BRCA1 and BRCA2 causative founder variants in ovarian cancer patients in South-East Poland.
Conclusions: The frequency of 13 causative founder variants in Podkarpacie was lower than in other regions of Poland. Testing of three BRCA1 mutations (c.5266dupC, c.181 T > G, c.676delT) should be considered a sensitive test panel.
PMID: 29492181 [PubMed]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Kluz T, Jasiewicz A, Marczyk E, Jach R, Jakubowska A, Lubiński J, Narod SA, Gronwald J Tags: Hered Cancer Clin Pract Source Type: research