Effects of a lifestyle intervention on psychosocial well-being of severe mentally ill residential patients: ELIPS, a cluster randomized controlled pragmatic trial

Large studies investigating the psychosocial effects of lifestyle interventions in patients with a severe mental illness (SMI) are scarce, especially in residential patients. This large, randomized controlled, multicentre pragmatic trial assessed the psychosocial effects of a combined diet-and-exercise lifestyle intervention targeting the obesogenic environment of SMI residential patients. Twenty-nine sheltered and clinical care teams were randomized into intervention (n=15) or control (n=14) arm.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research

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Publication date: Available online 16 March 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Katharina M. Kubera, Mahmoud Rashidi, Mike M. Schmitgen, Anja Barth, Dusan Hirjak, Fabio Sambataro, Vince D. Calhoun, Robert C. WolfAbstractThere is accumulating neuroimaging evidence for both structural and functional abnormalities in schizophrenia patients with persistent auditory verbal hallucinations (AVH). So far, the direct interrelationships between altered structural and functional changes underlying AVH are unknown. Recently, it has become possible to reveal hidden patterns of neural dys...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 22 November 2017Source: NeuroImageAuthor(s): Emmi Mikanmaa, Tineke Grent-'t-Jong, Lingling Hua, Marc Recasens, Hanna Thune, Peter J. UhlhaasAbstractThe identification of biomarkers for the early diagnosis of schizophrenia that could inform novel treatment developments is an important objective of current research. This paper will summarize recent work that has investigated changes in oscillatory activity and event-related potentials with Electro/Magnetoencephalography (EEG/MEG) in participants at high-risk for the development of schizophrenia, highlighting disruptions in sensory and cogni...
Source: NeuroImage - Category: Neuroscience Source Type: research
In this study, there was no significant relationship between disease genotype for DISC1 gene and schizophrenia. By increasing the heterozygote genotype in the population, the probability of the disease will increase and mutant homozygote genotypes will also be visible.
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
ConclusionsAsymmetric WM alterations were found in a frontal tract of patients with schizophrenia. Higher mean FA in the right frontal tract correlated with worse verbal memory performance, suggesting a possible contribution these brain changes to cognitive impairment in schizophrenia.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
I plead guilty to expounding on the biochemical vulnerabilities and abnormalities in neural wiring of depression to make the case that it is a legitimate illness alongside lupus, breast cancer, or psoriatic arthritis. I thought I was doing a good thing by quoting experts like Peter Kramer, M.D, who believes that because depression can be associated with the loss of volume in parts of the brain, it is the “most devastating disease known to mankind.” My intention, like so many other mental health advocates I know, was to use science as a tool to lessen stigma. But is that really effective? Proof of the Madness I ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior Depression General Mental Health and Wellness Psychiatry Psychology Research Self-Help Treatment biogenetic theory Depressive Episode Mental Illness Mood Disorder Stereotypes Stigma Source Type: blogs
In Reply We are gratified to know that the FDA is developing guidance that supports inclusion of individuals with suicidal ideation or behavior associated with serious mental illnesses, including schizophrenia and bipolar disorder, in clinical trials. We agree that trial participants with acute suicidal ideation or behavior, including those in the control groups of clinical trials evaluating suicidal ideation or behavior as an end point, be provided with standard-of-care (including emergency) interventions or with investigational approaches hypothesized to be as good as or better than the standard of care. However, mandati...
Source: JAMA - Category: General Medicine Source Type: research
This article will briefly review the clinical signs, symptoms and proposed etiologies of schizophrenia, and describe the current understanding of exercise programs as an effective treatment in patients with the disease. PMID: 30858639 [PubMed - in process]
Source: Psychopharmacology Bulletin - Category: Psychiatry & Psychology Tags: Psychopharmacol Bull Source Type: research
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Source: Journal of Mental Health - Category: Psychiatry Authors: Source Type: research
Publication date: Available online 14 March 2019Source: Social Science &MedicineAuthor(s): Saeko Kikuzawa, Bernice Pescosolido, Mami Kasahara-Kiritani, Tomoko Matoba, Chikako Yamaki, Katsumi SugiyamaAbstractAn extensive body of literature has documented the under-utilization of mental health services among Asian populations, regardless of where they live. Japan is one Asian country where the mental health care system has improved substantially in the recent decades. Yet, Japan continues to report greater under-utilization of mental health services than other developed countries. One primary reason for this is hypothesi...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
The objective of this study was to evaluate the convergent and divergent validity of four diagnose categories generated by the Schedule for Affective Disorders and Schizophrenia for School-Age Children - Present and Lifetime Version (K-SADS-PL). The diagnose categories were: anxiety, depression, attention deficit hyperactivity disorder (ADHD), and oppositional defiant disorder (ODD). The K-SADS-PL was applied in a clinical sample of youth aged 7-17 years (N = 269), who were participants in the Nordic long-term OCD-treatment study (NordLOTS). Youth and parents completed measures to evaluate symptoms of anxiety...
Source: Nordic Journal of Psychiatry - Category: Psychiatry Tags: Nord J Psychiatry Source Type: research
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