Outbreak of recombinant coxsackievirus A2 infection and polio-like paralysis of children, Taiwan, 2014

Patients with coxsackievirus A2 (CVA2) infection mostly present with herpangina and rarely have central nervous system complications.1 However, in 2012, a Hong Kong study reported that a naturally occurring recombinant CVA2 caused an outbreak of severe respiratory symptoms, leading to two deaths.2 In the current study, we report an outbreak of CVA2-infection-related acute flaccid paralysis (AFP) in Taiwan. Sequencing and analysis of the viruses isolated from fecal samples revealed that the currently prevalent CVA2 strain is highly similar to the Hong Kong recombinant.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Short Communication Source Type: research