Emotional context restores cortical prediction error responses in schizophrenia

The mismatch negativity (MMN) deficit in schizophrenia is a consistently replicated finding and is considered a potential biomarker. From the cognitive neuroscience perspective, MMN represents a cortical correlate of the prediction error, a fundamental computational operator that may be at the core of various cognitive and clinical deficits observed in schizophrenia. The impact of emotion on cognitive processes in schizophrenia is insufficiently understood, and its impact on basic operators of cortical computation is largely unknown.

Source: Schizophrenia Research - February 28, 2018 Category: Psychiatry Authors: Bob O. Vogel, Joanna Stasch, Henrik Walter, Andres H. Neuhaus Source Type: research