Anticholinergic Medications and Cognitive Function in Late Midlife.

Anticholinergic Medications and Cognitive Function in Late Midlife. Alzheimer Dis Assoc Disord. 2018 Feb 23;: Authors: Limback-Stokin MM, Krell-Roesch J, Roesler K, Hansen A, Stonnington CM, Temkit M, Caselli RJ, Geda YE PMID: 29481373 [PubMed - as supplied by publisher]
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research

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CLINICS IN GERIATRIC MEDICINE
Source: Clinics in Geriatric Medicine - Category: Geriatrics Authors: Source Type: research
Ultrasound can help researchers identify a dementia risk factor among older...Read more on AuntMinnie.comRelated Reading: AI helps uncover clues for Alzheimer's disease in MRI data Flortaucipir-PET targets tau for Alzheimer's diagnoses MRI links lifestyle factors to stroke, dementia risk PET could make synaptic density an Alzheimer's biomarker MRI links inflammation to cognitive decline
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
This study examined how longitudinal change in brain microstructure relates to cognitive decline in aging and prodromal Alzheimer's disease. At baseline and two-year follow-up, 29 healthy controls and 21 individuals with mild cognitive impairment or mild Alzheimer's disease underwent neuropsychological evaluation and restriction spectrum imaging (RSI). Microstructural change in the hippocampus, entorhinal cortex, and white matter tracts previously shown to be vulnerable to Alzheimer's disease, was compared between healthy controls and impaired participants. Partial correlations and stepwise linear regressions examined whet...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Middle-aged and worried about your memory slips? You probably don’t have dementia. The majority of the memory slips that concern this age group, and even those significantly older, are due to stress and other factors rather than impending dementia. However, researchers have now found that people who are suffering from memory loss but are unaware of their problem are most likely developing the disease. Read the full article on HealthCentral about awareness and memory loss - and how lack of  this awareness can point to developing dementia: MedicareFAQ – Medicare Resource Center Support a caregiver or jump-st...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
DiscussionSYGRAVA is the first randomized trial to determine whether programmable ASDs reduce complications of drainage compared to fixed ASDs in patients with iNPH. The results of this study may contribute to health-technology assessment of different valve systems used for VP-shunt surgery, and determination of the future standard of care.Trial registrationInternational Standard Randomised Controlled Trial Number:ISRCTN13838310. Registered on 10 November 2016.
Source: Trials - Category: Research Source Type: clinical trials
Cognitive change affecting patients after anaesthesia and surgery has been recognised for more than 100 yr. Research into cognitive change after anaesthesia and surgery accelerated in the 1980s when multiple studies utilised detailed neuropsychological testing for assessment of cognitive change after cardiac surgery. This body of work consistently documented decline in cognitive function in elderly patients after anaesthesia and surgery, and cognitive changes have been identified up to 7.5 yr afterwards. Importantly, other studies have identified that the incidence of cognitive change is similar after non-cardiac surgery. ...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
A new study has suggested that errors in DNA accumulated in a developing embryo may influence the risk of developing neurodegenerative diseases such as Alzheimer's later on in life.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
Publication date: February 2019Source: Journal of Neurolinguistics, Volume 49Author(s): Javier Rodríguez-Ferreiro, Carmen Martínez, Fernando CuetosAbstractAlzheimer's disease (AD) patients are known to present semantic memory impairments, and semantic processing plays a crucial role in the formation of false memories. We assessed 40 early stage AD patients and 35 matched healthy volunteers with an emotional version of the Deese-Roediger-McDermott paradigm, which allows the study of false memory formation. Participants were presented with three negative, three neutral and three positive lists of words, each se...
Source: Journal of Neurolinguistics - Category: Speech-Language Pathology Source Type: research
(MedPage Today) -- News and commentary from the world of neurology and neuroscience
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news
Publication date: Available online 15 October 2018Source: Alzheimer's &DementiaAuthor(s): Kwangsik Nho, Alexandra Kueider-Paisley, Siamak MahmoudianDehkordi, Matthias Arnold, Shannon L. Risacher, Gregory Louie, Colette Blach, Rebecca Baillie, Xianlin Han, Gabi Kastenmüller, Wei Jia, Guoxiang Xie, Shahzad Ahmad, Thomas Hankemeier, Cornelia M. van Duijn, John Q. Trojanowski, Leslie M. Shaw, Michael W. Weiner, P. Murali Doraiswamy, Andrew J. SaykinAbstractIntroductionBile acids (BAs) are the end products of cholesterol metabolism produced by human and gut microbiome co-metabolism. Recent evidence suggests gut microbi...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
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