Beta cell regeneration can be stimulated in the pancreas
Progenitor cells located in the human pancreas can be primed to become beta cells, potentially becoming a new therapeutic option for type-1 diabetes patients, according to a study inCell Reports.Science Daily
Condition: Type 1 Diabetes Mellitus Interventions: Device: AID System; Drug: Insulin Lispro Sponsor: Eli Lilly and Company Not yet recruiting
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Coinciding with World Diabetes Day, the National Health Service (NHS) in England is providing funding for Flash Glucose Monitors (FGM) for Type 1 Diabetic (T1D) patients. The move is set to change the lives of tens of thousands of people in the country.
Conclusions: The reactivity to VEGF inhibitors varied among different subtypes of nAMD. The efficacy of intravitreal anti-VEGF therapy in type 3 nAMD was statistically better than type 1 when considering vision improvement at 3 and 12 months. Thus, the lesion subtype is a predictor for the treatment outcome which can help guide prognosis. PMID: 30425852 [PubMed]
Jane E. Yardley, Nicole K. Brockman, Richard M. Bracken
ConclusionsOverall, two thirds of the pediatric T2DM guidelines were moderate to low quality and the remaining third ranked higher in quality. Low quality was especially due to the scores for the “Rigour of Development” domain, which directly measures guideline development methodology. It is important that future guidelines and updates of existing guidelines improve the methodology of development and quality of reporting in order to appropriately guide physicians managing children and ad olescents with T2DM.Systematic review registrationPROSPEROCRD42016034187
This article reviews recent studies in both diabetic patients and in these animal models, and discusses novel hypotheses to delineate the increased incidence of heart failure in diabetic patients.
Tens of thousands of people with type 1 diabetes across the country will benefit from life changing glucose monitors on the NHS.