Antibacterials: Synthetic peptides eradicate resistant infections

Nature Reviews Drug Discovery 17, 166 (2018). doi:10.1038/nrd.2018.31 Author: Sarah Crunkhorn Synthetic peptides based on naturally occurring antimicrobial peptides (AMPs) represent promising antibacterial agents. Now, de Breij and colleagues have synthesized novel peptides with improved antimicrobial and antibiofilm activities (SAAPs), based on a principle human AMP, LL-37. The most potent of these, SAAP-148, was effective against
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research