Female Infertility Tied to Asthma Managed With Rescue Inhalers

No link to infertility for those with former asthma, or for those with asthma preventer medications
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Family Medicine, Gynecology, Internal Medicine, Allergy, Pharmacy, Pulmonology, Journal, Source Type: news

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Publication date: Available online 21 October 2018Source: Life SciencesAuthor(s): Ivan Mrkić, Rajna Minić, Dragan Popović, Irena Živković, Marija Gavrović-JankulovićAbstractAimTo investigate the immunomodulatory potential of a chimera composed of the receptor-binding domain of hemagglutinin 1 (H1s) from Influenza virus and Der p 2 (D2) allergen for allergen-specific immunotherapy of house-dust mite allergy (HDM).Main methodsH1sD2 chimera and D2 allergen were produced by genetic engineering in E. coli. Recombinant antigens were extracted from inclusion bodies by urea, then refolded and purified by immobilized- metal ...
Source: Life Sciences - Category: Biology Source Type: research
In this study, we prepared bone marrow-derived mast cells from BALB/c and C57BL/6 mice and examined their cellular properties. Cellular response to IL-3 and the process of mast cell differentiation from bone marrow cells were different on the basis of cell surface marker molecules. BALB/c-derived cells more efficiently exhibited degranulation than did C57BL/6-derived cells following both calcium ionophore and receptor crosslinking. These functional differences persisted even after a longer cell culture for 8 weeks, suggesting a difference in cell-autonomous characteristics. These results support the concept that mast ...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Authors: Levin G, Rottenstreich A Abstract Pituitary disorders, and especially prolactinomas, are not common among pregnant women, though they tend to occur during a woman's years of fertility. The majority of prolactinoma patients present with infertility and menstruation dysfunction; however, prolactinomas are associated with potentially significant morbidity if they remain unrecognized and untreated. Herein, we survey the role of prolactin and prolactinomas in pregnancy while also outlining the therapeutic approach to prolactinoma during pregnancy. The current literature on the impact of dopamine agonists during...
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
CONCLUSIONS: We found that the majority of human milk samples included beta-lactams or quinolones, even though the mothers did not receive these antibiotics during pregnancy and lactation. Antibiotic residues in human milk may affect early maintenance of the intestinal microbiota. Previous studies have shown that antimicrobials in food might increase the risks of allergies and could lead to the development of antibiotic-resistant bacterial strains. Effective policies on food safety and appropriate antibiotic use during pregnancy and lactation are needed. PMID: 30338827 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
ConclusionMost potent three chemicals (ZA-2, 6 and 7) could be considered as bioactive to ensure the robust quality of the enriched fraction of ZAF with defined XO inhibition potential. Therefore, either single purified component or their enriched fraction could be a better choice for the management of gout than the crude extract of ZAF. Developed HPLC method is suitable for quality assurance analysis and process control of ZAF derived product intended for gout management. XO inhibitory potential exhibited by the characterized compounds validate the traditional use of this ZAF for the treatment of gout. Further, a detailed...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Evidence is increasing of an association between asthma and aspects of female reproduction. However, current knowledge is limited and furthermore relies on questionnaire studies or small populations. In a prospective observational cohort study to investigate whether time to pregnancy, the number of fertility treatments, and the number of successful pregnancies differ significantly between women with unexplained infertility with and without asthma. 245 women with unexplained infertility (aged 23–45 years) underwent questionnaires and asthma and allergy testing while undergoing fertility treatment. 96 women enteri...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Asthma and allergy Original Articles: Asthma Source Type: research
SPECIAL FROM You may watch what you eat, drink filtered water, and use your seat belt to protect yourself on the road. Yet many health hazards are lurking around us in not-so-obvious places. Here, a few to steer clear of:  1. Scented candles A fragrant candle may help you unwind and de-stress. But burning those containing a chemical calledlimonene, often used for citrus-scented candles, as well as many cleaning products, can produce fumes that are downright unhealthy. Recent British research found that households with a high levels of limonene correlated with high levels of formaldehyde, which irritates the eyes and ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Conclusion A growing number of today’s children suffer from vaccine damage. Most individuals do not make the connection between health problems and vaccines. When asked about the cause of autoimmune disorders, asthma, allergies, diabetes, learning disabilities, attention deficit disorder, autism, and other common childhood diseases and illness, the majority of health care providers advise patients that the causes are unknown. Doctors, including most integrative physicians, fail to make the connection to vaccines. It takes one moment to permanently damage the health of an adult or child, but t...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Logical Michelle Goldstein Top Stories autoimmune disorders gardasil HPV Vaccine Medical Authority vaccine injury Source Type: blogs
This study investigated the association between HLA-G  gene  polymorphism  with repeated implantation failure (RIF). We used PCR followed by the sequencing technique for exons 2, 3, and 4, as well as intron 2 of the HLA-G gene in 100 couples with histories of two or more failed assisted reproductive technique (ART) attempts. The data were compared with the results of our previous study.The results indicated that some alleles of the HLA-G gene such as: 0106, 010106, 01010106 and 0105N (null) alleles were significantly higher in the patient group compared to the control group (p
Source: Iranian Journal of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Iran J Allergy Asthma Immunol Source Type: research
This study was funded by the University Hospital of Oulu and Helsinki, Finland. The National Institute for Health and Welfare (THL) covered the data linkages and the work of Mika Gissler. There are no competing interests to be reported.
Source: Human Reproduction - Category: Reproduction Medicine Authors: Tags: Reproductive epidemiology Source Type: research
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