Factor analysis of regional brain activation in bipolar and healthy individuals reveals a consistent modular structure

The neurophysiological substrates of cognition and emotion, as seen with fMRI, are generally explained using modular structures. The present study was designed to probe the modular structure of cognitive-emotional processing in bipolar and healthy individuals using factor analysis and compare the results with current conceptions of the neurophysiology of bipolar disorder.

Source: Journal of Affective Disorders - February 27, 2018 Category: Neurology Authors: David E. Fleck, Jeffrey A. Welge, James C. Eliassen, Caleb M. Adler, Melissa P. DelBello, Stephen M. Strakowski Source Type: research