Yale Medicine plastic surgeon helps repair self-esteem

In addition to repairing damaged tissue and reconstructing faces, Dr. Yan Ho Lee ’s work goes beyond appearance to help restore confidence in her patients.
Source: Yale Science and Health News - Category: Universities & Medical Training Source Type: news

Related Links:

Publication date: Available online 13 December 2018Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Martin Kaufmann, Corine Martineau, Alice Arabian, Mary Traynor, René St-Arnaud, Glenville JonesAbstractCalcitroic acid, the excretory form of vitamin D, is the terminal product of a 5-step pathway catalyzed by CYP24A1, commencing with C24-hydroxylation of 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). Catabolism of 25-hydroxyvitamin D3 (25-OH-D3) proceeds via analogous steps culminating in calcioic acid; however this C23-truncated acid has not been reported in the circulation. It has recently been...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Publication date: Available online 13 December 2018Source: The Journal of Foot and Ankle SurgeryAuthor(s): Anthony Tickner, Seiha Thorng, Mary Martin, Valerie MarmolejoAbstractRupture of the tibialis anterior tendon is a rare condition reported to occur most often spontaneously in patients>45 years of age. Diagnosis is often delayed due to transient pain at the time of rupture and the ability of the long extensors to compensate for the lost action of the tibialis anterior. Treatment has been proposed to be based on the activity level of the individual; however, no consensus has been reached on the optimal treatment moda...
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
Conditions:   High Risk Pregnancy;   Congenital Heart Disease;   Fetal Hydrops;   Twin Monochorionic Monoamniotic Placenta;   Gastroschisis;   Fetal Demise;   Stillbirth;   Fetal Arrhythmia;   Long QT Syndrome;   Intrauterine Fetal Death;   Sudden Infant Death;   Pregnancy Loss;   Twin Twin Transfusion Syndrome;   Birth Defect;   Fetal Cardiac Anomaly;   Fetal Cardiac Disorder;   Fetal Death;   Brugada ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Nerve-repair startup Renerva said today it has received $2.4 million in funding from the U.S. Department of Defense. The Pittsburgh company is developing a periheral nerve matrix (PNM), an injectable gel derived from porcine tissue to help repair and regenerate injured peripheral nerves. The Medical Technology Enterprise Consortium (MTEC) Award award will enable Renerva to complete its preclinical program and begin human clinical trials. PNM has the potential to play a significant role in accelerating and improving structural and functional recovery following different modalities of nerve injury, according t...
Source: Mass Device - Category: Medical Devices Authors: Tags: Blog Business/Financial News Funding Roundup Neurological News Well Research & Development cornelluniversity medical technology enterprise consortium renerva University of Pittsburgh Source Type: news
Publication date: Available online 13 December 2018Source: CellAuthor(s): Kareem N. Mohni, Sarah R. Wessel, Runxiang Zhao, Andrea C. Wojciechowski, Jessica W. Luzwick, Hillary Layden, Brandt F. Eichman, Petria S. Thompson, Kavi P.M. Mehta, David CortezSummaryAbasic sites are one of the most common DNA lesions. All known abasic site repair mechanisms operate only when the damage is in double-stranded DNA. Here, we report the discovery of 5-hydroxymethylcytosine (5hmC) binding, ESC-specific (HMCES) as a sensor of abasic sites in single-stranded DNA. HMCES acts at replication forks, binds PCNA and single-stranded DNA, and gen...
Source: Cell - Category: Cytology Source Type: research
Authors: Kaul G, Kapoor E, Dasgupta A, Chopra S Abstract Delafloxacin meglumine (Baxdela, WQ-3034, ABT-492, RX-3341; Melinta Therapeutics) was approved by the U.S. Food and Drug Administration (FDA) in June 2017 for the treatment of acute bacterial skin and skin structure infections on the basis of data from two phase III trials. Delafloxacin is a broad-spectrum anionic fluoroquinolone and its distinct chemical structure increases its potency in acidic environments. It is known to inhibit DNA replication and repair by targeting DNA gyrase and topoisomerase IV. Delafloxacin is administered via both oral and parenter...
Source: Drugs of Today - Category: Drugs & Pharmacology Tags: Drugs Today (Barc) Source Type: research
We report two cases of interrupted right aortic arch associated with isolated left pulmonary artery and bilateral ductus arteriosus in the first case and with truncus arteriosus in the second case. Computed tomography was complementary to echocardiography in delineating the anatomic details in both cases, informing surgical repair with reconstruction of a left aortic arch in the first case and right arch in the second case.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
We present a challenging patient with a rapidly enlarging left ventricular pseudoaneurysm 4 weeks after coronary bypass. The repair was approached through a left thoracotomy using circulatory arrest with selective antegrade cerebral perfusion.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsRepair of CoA, even with associated transverse arch hypoplasia, by REEEA through left thoracotomy has a low mortality, low reintervention rate, and low incidence of late hypertension.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
This study examined outcomes of a cohort undergoing a first M-MVR at age younger than 21 years.MethodsWe queried the Pediatric Cardiac Care Consortium, a multi-institutional United States-based cardiac intervention registry, for patients undergoing first M-MVR for 2-ventricle congenital heart disease. Survival and transplant status through 2014 were obtained from Pediatric Cardiac Care Consortium and linkage with the National Death Index and the Organ Procurement and Transplantation Network.ResultsWe identified 441 patients (median age, 4.3 years; interquartile range, 1.3 to 10.1 years) meeting study criteria. The commones...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
More News: Gastroschisis Repair | Plastic Surgery | Science | Universities & Medical Training | Yale