Proof-of-concept study reveals feasibility of eliminating rabies in Africa

(Institut Pasteur) The Swiss Tropical and Public Health Institute, together with European and African collaborators (including the Institut Pasteur in Paris), carried out a mass dog vaccination in Chad and determined its effect on human rabies exposure. The study employed a bio-mathematical method for estimating the transmission dynamics of rabies. The researchers conclude that with political will and the necessary funding, elimination of rabies is possible in Africa.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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mplementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and BeyondAir date: 10/17/2018 8:23:00 AM
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
Authors: Beaman MH Abstract Meningitis and encephalitis are medical emergencies. Patients need prompt evaluation and immediate empiric therapy to reduce the likelihood of fatal outcomes and chronic neurological sequelae. Conjugate bacterial vaccines have significantly reduced the incidence of bacterial meningitis, especially in children. As the results of changes in patterns of bacterial drug sensitivity, ceftriaxone is now part of the recommended empiric treatment for bacterial meningitis and should be administered as early as possible. Neuroimaging delays the treatment of meningitis and is not needed in most case...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Publication date: Available online 11 October 2018Source: Veterinary MicrobiologyAuthor(s): Dimos P. Papatheodorou, Konstantia E. Tasioudi, Laskarina-Maria Korou, Vasileios L. Georgiou, Gerasimos Markantonatos, Peristera Iliadou, Aikaterini Kirtzalidou, Aggeliki Katsifa, Spyridon Ztrivas, Georgia Bechtsi, Myrsini Tzani, Eleni Chondrokouki, Olga Mangana-VougioukaAbstractAlthough juvenile red foxes (Vulpes vulpes) are considered a single age group, essential for monitoring the effectiveness of the oral rabies vaccination (ORV), there appear to be significant differences among age subgroups. Herein, a subset of 335 foxes aged...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
A new vaccine showed preclinical promise at effectively protecting people from Lassa fever and rabies in a study involving mice and guinea pigs.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
The inactivated recombinant vaccine candidate uses a weakened rabies virus vector.
Source: National Institutes of Health (NIH) News Releases - Category: American Health Source Type: news
(Thomas Jefferson University) A new Lassa fever and rabies vaccine shows lasting immunity and suggests a new way to test for protection.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(NIH/National Institute of Allergy and Infectious Diseases) A novel vaccine designed to protect people from both Lassa fever and rabies showed promise in preclinical testing, according to new research published in Nature Communications. The investigational vaccine, called LASSARAB, was developed and tested by scientists at Thomas Jefferson University in Philadelphia; the University of Minho in Braga, Portugal; the University of California, San Diego; and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
This study estimated the economic burden of canine rabies in a societal perspective including direct and indirect cost of rabies in dogs, livestock, and humans. Using data collected from personal interviews, published literature, published and supplementary reports, and primary data collection, we estimated the economic impact of canine rabies in Viet Nam over a ten year period (2005–2014). We incorporated the direct and indirect costs for PEP, dog vaccination efforts, livestock losses, and disability adjusted life years (DALYs) int o the analysis. General findings from this analysis indicated that over the 10 year s...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
CONCLUSION: PEP access could be improved and rabies deaths reduced through ring-fenced procurement, switching to dose-sparing ID regimens and free provision of PEP. PMID: 30309746 [PubMed - as supplied by publisher]
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Publication date: 29 September–5 October 2018Source: The Lancet, Volume 392, Issue 10153Author(s): Barbara L Zimmer, Luke Gamble, Dagmar Mayer, Rachel Foster, Josephine Langton
Source: The Lancet - Category: General Medicine Source Type: research
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