Integrative treatment package for degenerative disc disease in the lumbar spine: a retrospective case series.

Conclusions This study describes the use of acupuncture-related modalities and raises the possibilities of their use in combination therapy for the improvement of function and pain management in patients with DDD. In light of these promising results, future clinical trials with attention to appropriate patient selection, guidelines for integrative treatment, and optimal standards for outcome measurement are necessary to evaluate the effectiveness of integrative treatment.
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research

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The lumbar paraspinal muscles, including the erector spinae and multifidus, play an important role in movement and control of the spine. However, our understanding of their contribution to low back pain and disability is unclear. Systematic reviews have reported conflicting evidence for an association between paraspinal muscle size and low back pain, and a paucity of data examining muscle cross-sectional area and low back disability.
Source: The Spine Journal - Category: Orthopaedics Authors: Tags: Clinical Study Source Type: research
ConclusionIn this retrospective analysis, TENS has no predictive value in the selection of patients with low back pain for the PFNS treatment. PNFS is effective and safe to relieve significantly symptoms of chronic low back pain.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Clinical Research Source Type: research
DiscussionThis trial may help inform further research on biological mechanisms related to manual therapies employed by chiropractic practitioners.Trial,NCT02670148 Registered on 1 February 2016.
Source: Trials - Category: Research Source Type: clinical trials
ConclusionsThe healthy lifestyle intervention seems to be cost ‐effective from the societal perspective. However, variability in the sensitivity analyses indicates caution is needed when interpreting these findings.SignificanceThis is an economic evaluation of a randomized controlled trial of a healthy lifestyle intervention for chronic low back pain. The findings suggest that a healthy lifestyle intervention may be cost ‐effective relative to usual care.
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Subgrouping patients with chronic low back pain is recommended prior to selecting treatment strategy, and fear avoidance beliefs is a commonly addressed psychological factor used to help this subgrouping. The ...
Source: BMC Musculoskeletal Disorders - Category: Orthopaedics Authors: Tags: Research article Source Type: research
Conclusion. Increased ADD occurred with similar frequency after TDR and after nonoperative treatment, and was not related to the clinical outcome at 8-year follow-up. Level of Evidence: 1
Source: Spine - Category: Orthopaedics Tags: RANDOMIZED TRIAL Source Type: research
AbstractLow back and neck pain are among the top contributors for years lived with disability, causing patients to seek substantial non-operative and operative care. Intervertebral disc herniation is one of the most common spinal pathologies leading to low back pain. Patient comorbidities and other risk factors contribute to the onset and magnitude of disc herniation. Spine fusions have been the treatment of choice for disc herniation, due to the conflicting evidence on conservative treatments. However, re-operation and costs have been among the main challenges. Novel technologies including cage surface modifications, biol...
Source: International Orthopaedics - Category: Orthopaedics Source Type: research
Authors: Veihelmann A Abstract BACKGROUND: Many members of the adult population suffer acute low back pain at some stage in life. A specific cause is found in only a rather small number of these patients. Some of the patients develop chronic low back pain and this is a major source of disability. On the other hand, there has been a great increase in Germany in the number of spinal operations due to degenerative spine disease and, in turn, unnecessary surgery on the spine is under debate. METHODS: This is a narrative review of different minimally invasive spine procedures in the treatment of specific low back pa...
Source: Zeitschrift fur Orthopadie und Unfallchirurgie - Category: Orthopaedics Tags: Z Orthop Unfall Source Type: research
AbstractIntervertebral disc (IVD) degeneration (IDD) is considered as one of the major causes for low back pain (LBP). However, conventional surgical approaches for treating LBP do not aim to counter the degeneration. Biological interventions have been investigated with an attempt to regenerate the IVD by restoring its matrices and cell activities. This review summarizes the current clinical trials that explore the efficacy of covering cell-, growth factor-, and small molecule-based approaches. While investigations of growth factor- and small molecule-based therapies are still preliminary, intradiscal delivery of mesenchym...
Source: International Orthopaedics - Category: Orthopaedics Source Type: research
AbstractLow back pain is the primary cause of disability and is highly associated with progression of intervertebral disc degeneration. Current treatment options are limited and fail to address the origin of the problem. New advancements in cellular therapies might offer novel and potent strategies for low back pain patients. In this review, we summarize and discuss the contemporary status of in-human trials investigating cellular transplantation for treatment of low back pain. We aim to highlight current trends, shortcomings, and hurdles for effective clinical trials and consecutive commercialization.
Source: International Orthopaedics - Category: Orthopaedics Source Type: research
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