Cystic fibrosis epithelial cells are primed for apoptosis as a result of increased Fas (CD95)

Previous work suggests that apoptosis is dysfunctional in cystic fibrosis (CF) airways with conflicting results. We evaluated the relationship between dysfunctional cystic fibrosis transmembrane conductance regulator (CFTR) and apoptosis in CF airway epithelial cells.

Source: Journal of Cystic Fibrosis - February 24, 2018 Category: Respiratory Medicine Authors: Qiwei Chen, Sudha Priya Soundara Pandi, Lauren Kerrigan, Noel G. McElvaney, Catherine M. Greene, J. Stuart Elborn, Clifford C. Taggart, Sin éad Weldon Tags: Original Article Source Type: research