Effects of short-term, high-frequency repetitive transcranial magnetic stimulation to bilateral dorsolateral prefrontal cortex on smoking behavior and cognition in patients with schizophrenia and non-psychiatric controls

High rates of tobacco smoking and smoking cessation failure in schizophrenia may be related to prefrontal cortical dysfunction. Novel treatment options for tobacco use disorder are needed given the limited efficacy of current pharmacotherapies. Preliminary evidence suggests high-frequency repetitive transcranial magnetic stimulation (rTMS) to bilateral dorsolateral prefrontal cortex (DLPFC) may suppress tobacco craving in smokers with schizophrenia. The goal of this study was to determine effects of rTMS for tobacco craving and cognition using a short-term (3-day) human laboratory paradigm.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research

Related Links:

Date: Tuesday, 03 26, 2019; Speaker: Dr. Manzure Mawla; Dr. David Lewis, University of Pittsburgh, Department of Psychiatry; Building: Building 10 (Clinical Center); Lipsett Auditorium; CME Credit
Source: NIH Calendar of Events - Category: American Health Source Type: events
Conclusions: Lifetime cannabis use is associated with better working memory and processing speed and worse real-world functioning in the area of socially useful activities in patients with schizophrenia-related disorders. Clinicians should, therefore, be aware of it to provide patient-centred care in their daily clinical practice.Eur Addict Res 2019;25:111 –118
Source: European Addiction Research - Category: Addiction Source Type: research
Publication date: Available online 21 March 2019Source: Schizophrenia Research: CognitionAuthor(s): D.H.V. Vogel, T. Beeker, T. Haidl, C. Kupke, M. Heinze, K. VogeleyAbstractDisturbances in time experience have been argued to play a significant, if not causative role in the clinical presentation of schizophrenia. Phenomenological considerations suggest a fragmented or dis-articulated time experience causing both primary symptoms such as hallucinations, delusions, and self-disorders, as well as an intersubjective desynchronization. We employed content analysis on material collected from patients diagnosed with schizophrenia...
Source: Schizophrenia Research: Cognition - Category: Psychiatry Source Type: research
The objective of this review is to comprehensively assess the literature on metabolomics in mood disorders and schizophrenia and provide data for mental health researchers about the challenges and potentials of metabolomics. The majority of studies in metabolomics in Psychiatry uses peripheral blood or urine. The most widely used analytical techniques in metabolomics research are nuclear magnetic resonance (NMR) and mass spectrometry (MS). They are multiparametric and provide extensive structural and conformational information on multiple chemical classes. NMR is useful in untargeted analysis, which focuses on biosignature...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 20 March 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Chuanjun Zhuo, Weihong Hou, Gongying Li, Fuqiang Mao, Shen Li, Xiaodong Lin, Deguo Jiang, Yong Xu, Hongjun Tian, Wenqiang Wang, Langlang ChengAbstractDue to recent advances in human genomic technologies, there have been explosive interests and extensive research on the genomics of schizophrenia, a severe psychiatric disorder characterized by social cognitive deficits, hallucinations, and delusions. These new technologies, including next-generation sequencing (NGS), genome-wide association studies...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 21 March 2019Source: Journal of Psychiatric ResearchAuthor(s): Nicole R. DeTore, Kim T. Mueser, Jessica A. Byrd, Susan R. McGurkAbstractCognitive remediation is aimed at reducing cognitive impairments in severe mental illnesses such as schizophrenia, but little is known about whether severity of cognitive impairment predicts benefit from this intervention. To address this question, this study aggregated data from five randomized controlled trials (N=300) of a standardized comprehensive, multimodal outpatient cognitive remediation program, the Thinking Skills for Work program, and evaluate...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Series Type : Methylation profiling by arrayOrganism : Homo sapiensWe analyzed fresh frozen post-mortem brain tissue from a cohort of 73 schizophrenic and 52 control samples, using the Illumina Infinium HumanMethylation450 Bead Chip, to investigate genome-wide DNA methylation patterns in patients diagnosed with schizophrenia.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Methylation profiling by array Homo sapiens Source Type: research
CONCLUSIONS: The SH staff was able to produce valid FAST-O assessments. There are reference data which makes it possible to characterize individual patients as well as SH units with respect to treatment needs and safety aspects (for instance risk of violence). PMID: 30888234 [PubMed - as supplied by publisher]
Source: Nordic Journal of Psychiatry - Category: Psychiatry Tags: Nord J Psychiatry Source Type: research
Authors: Faivre S, Roche N, Lacerre F, Dealberto MJ Abstract OBJECTIVES: The main objective of the study was to assess 25-hydroxyvitamin D (25(OH)D) status in a psychiatric population in France according to psychiatric diagnoses. The secondary objective was to investigate a correlation between 25(OH)D and CRP. METHODS: A retrospective study from February 1st, 2014 to January 31, 2016, was carried out in a French psychiatric hospital. Inpatients with a 25(OH)D measure were included. Variables including ethnic origin, BMI, psychiatric diagnoses, medical history and CRP were collected. Factors associated with 25(O...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
Conditions:   Schizophrenia;   Psychotic Disorders;   Psychosis Interventions:   Drug: Aripiprazole;   Drug: Risperidone Sponsors:   Fundación Marques de Valdecilla;   Centro de Investigación Biomédica en Red de Salud Mental;   Instituto de Investigación Marqués de Valdecilla Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Laboratory Medicine | Psychiatry | Schizophrenia | Smokers | Study