TNF- α promotes colon cancer cell migration and invasion by upregulating TROP-2.

In conclusion, the present results demonstrated that low concentrations of TNF-α significantly enhanced colon cancer cell migration and invasion by upregulating TROP-2 via the ERK1/2 signaling pathway. PMID: 29467899 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/29467899?dopt=Abstract

Source: Oncology Letters - February 24, 2018 Category: Cancer & Oncology Tags: Oncol Lett Source Type: research