Human Periodontal Ligament ‐derived Stem Cells Promote Retinal Ganglion Cell Survival and Axon Regeneration after Optic nerve injury

This study demonstrated that human periodontal ligament‐derived stem cells (PDLSCs) reduce retinal ganglion cells (RGC) degeneration induced by optice nerve injury and promote axon regeneration in rats. Human PDLSCs also en‐hance RGC survival and neurite outgrowth in the retinal explant culture model through direct PDLSC‐RGC interaction and neurotrophic factor secretion from human PDLSCs.

Source: Stem Cells - February 24, 2018 Category: Stem Cells Authors: Ling ‐Ping Cen, Tsz Kin Ng, Jia‐Jian Liang, Xi Zhuang, Xiaowu Yao, Gary Hin‐fai Yam, Haoyu Chen, Herman S. Cheung, Mingzhi Zhang, Chi Pui Pang Tags: Regenerative Medicine Source Type: research