Maturation of the Coordination Between Respiration and Deglutition with and Without Recurrent Laryngeal Nerve Lesion in an Animal Model
AbstractThe timing of the occurrence of a swallow in a respiratory cycle is critical for safe swallowing, and changes with infant development. Infants with damage to the recurrent laryngeal nerve, which receives sensory information from the larynx and supplies the intrinsic muscles of the larynx, experience a significant incidence of dysphagia. Using our validated infant pig model, we determined the interaction between this nerve damage and the coordination between respiration and swallowing during postnatal development. We recorded 23 infant pigs at two ages (neonatal and older, pre-weaning) feeding on milk with barium using simultaneous high-speed videofluoroscopy and measurements of thoracic movement. With a complete linear model, we tested for changes with maturation, and whether these changes are the same in control and lesioned individuals. We found (1) the timing of swallowing and respiration coordination changes with maturation; (2) no overall effect of RLN lesion on the timing of coordination, but (3) a greater magnitude of maturational change occurs with RLN injury. We also determined that animals with no surgical intervention did not differ from animals that had surgery for marker placement and a sham procedure for nerve lesion. The coordination between respiration and swallowing changes in normal, intact individuals to provide increased airway protection prior to weaning. Further, in animals with an RLN lesion, the maturation process has a larger effect. Finally, ...
Authors: Mendoza De La Garza M, Tieu C, Schroeder D, Lowe K, Tung E Abstract Medical schools throughout the country struggle with how best to train students to provide quality, patient-centered care to the burgeoning population of older adults. The Senior Sages Program (SSP) is a longitudinal Senior Mentor Program (SMP) that offers students the opportunity to learn about the aging process and core geriatric medicine concepts through the eyes of an aging expert: their Senior Sage. The SSP marries a robust electronic curriculum with an SMP and online discussion board. The aim of this program evaluation was to measure...
A single hailstorm changed me from rational to irrational... The post How to Use Framing to Sell More Warranties and Service Contracts appeared first on Neuromarketing.
Discussion When men enacted female-typical caregiving roles, their retirement timing resembled women's. Eldercare, in particular, was associated with earlier retirement timing. Implications for individual retirement decision-making and policy are discussed. PMID: 29911387 [PubMed - as supplied by publisher]
The former Tory leader has urged his party to consider legalising recreational use of the drug.
According to Toronto-based scholar Dr Jeanette Bicknell from York University, people's feelings about their use of time contributes to wellbeing as much as their wealth.
STOMACH bloating is caused by eating something that your stomach disagrees with, or something that you're allergic to. It involves a swelling in the stomach which can be painful. Juicing guru, Jason Vale, recommended trying this drink on ITV's This Morning to help beat the bloat.
LONDON (Reuters) - Britain said on Tuesday it had no intention of legalizing cannabis after a former leader of Prime Minister Theresa May's party said the government had "irreversibly lost" the battle to drive the drug off the streets.
Researchers from the Centers for Disease Control and Prevention in Atlanta, Georgia, found HIV tests can give false negative results for up to seven months among those taking PrEP.
CONCLUSION: Childhood cholesteatoma was more extensive and destructive compared to adults, representing a more aggressive disease in this cohort. PMID: 29909808 [PubMed - as supplied by publisher]
CONCLUSION: The results show a good correlation between the pre-operatively predicted insertion depths using the software application and those post-operatively measured using X-ray. The insertion length predicted by the software was always longer than that measured via X-ray. PMID: 29909807 [PubMed - as supplied by publisher]